Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters.
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Summary
It is hypothesized that the increase in plasma BA is an early event in the progression of CRF and is caused by increased efflux across the basolateral hepatocyte membrane.
- Type
- article
- Published
- 2014-01-01
- Cited by
- 48
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W24197062
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27875793
Keywords
Minimalism (technical communication), Repetition (rhetorical device), Art, Visual arts, Composition (language)
References
- Chronic Renal Failure-Induced Changes in Serum and Urine Bile Acid Profiles
- Influence of Serum in Hemodialysis Patients on the Expression of Intestinal and Hepatic Transporters for the Excretion of Pravastatin
- Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat.
- Deciphering the nuclear bile acid receptor FXR paradigm
- Bile acid synthesis from cholesterol: regulatory and auxiliary pathways
- Atherogenic lipids and lipoproteins in hemodialysis patients.
- Glucose and insulin metabolism in uremia.
- Fat redistribution and adipocyte transformation in uninephrectomized rats.
- Characterization of the passive and active transport mechanisms for bile acid uptake into rat isolated intestinal epithelial cells.
- TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading
- Differential regulation of basolateral and canalicular transporter expression in rat liver in chronic renal failure
- A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.
- Mechanisms of Hepatic Transport of Drugs: Implications for Cholestatic Drug Reactions
- TGR5: A Novel Target for Weight Maintenance and Glucose Metabolism
- Effects of Chronic Renal Failure on Liver Drug Transporters
- The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation
- Uninephrectomy of Diabetic OVE26 Mice Greatly Accelerates Albuminuria, Fibrosis, Inflammatory Cell Infiltration and Changes in Gene Expression
- Molecular mechanisms of altered cholesterol metabolism in rats with spontaneous focal glomerulosclerosis.
- Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7 alpha-hydroxylase in rats with subtotal nephrectomy.
- Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR.
Cited by
- CHARACTERIZATION OF THE EFFECT OF CHRONIC KIDNEY DISEASE ON HEPATIC DRUG REDUCTION: IN-VITRO AND IN-VIVO STUDIES OF WARFARIN
- Uninephrectomy in rats on a fixed food intake results in adipose tissue lipolysis implicating spleen cytokines
- CYP3A5 polymorphism affects the increase in CYP3A activity after living kidney transplantation in patients with end stage renal disease.
- Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney.
- The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes
- Mechanism underlying an elevated serum bile acid level in chronic renal failure patients
- Associations of trimethylamine-N-oxide (TMAO) with nutritional and inflammatory biomarkers and cardiovascular outcomes in patients new to dialysis
- Simultaneous determination of loganin, morroniside, catalpol and acteoside in normal and chronic kidney disease rat plasma by UPLC-MS for investigating the pharmacokinetics of Rehmannia glutinosa and Cornus officinalis Sieb drug pair extract.
- Uninephrectomy in Rats on a Fixed Food Intake Potentiates Both Anorexia and Circulating Cytokine Subsets in Response to LPS
- Uninephrectomy-Induced Lipolysis and Low-Grade Inflammation Are Mimicked by Unilateral Renal Denervation
- Preventive and Curative Effects of Zingiber officinale Extract against Histopathological and Ki-67 Immunohistochemical Changes of Glycerol-Induced Acute Renal Failure in Rat
- Non-invasive visualisation and quantification of (disturbed) hepatobiliary transport
- TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice
- PBPK Modeling of the Effect of Reduced Kidney Function on the Pharmacokinetics of Drugs Excreted Renally by Organic Anion Transporters
- Deoxycholic Acid, a Metabolite of Circulating Bile Acids, and Coronary Artery Vascular Calcification in CKD
- Protective and antioxidant effects of copper-nicotinate complex against glycerol-induced nephrotoxicity in rats
- Definitive profiling of plasma bile acids as potential biomarkers for human liver diseases using UPLC-HRMS.
- Factors involved in phenoconversion of CYP3A using 4β-hydroxycholesterol in stable kidney transplant recipients
- The role of chronic kidney disease-associated dysbiosis in cardiovascular disease
- The decreased SIRT1 level may account for the lipid profile in chronic kidney disease
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