Quercetin: a pleiotropic kinase inhibitor against cancer.
Explore this paper's citation graph
Summary
The ability of the molecule to inhibit protein kinases involved in deregulated cell growth in cancer cells is reviewed, and the use of natural or synthetic compounds able to stop, reverse, or delay the process of tumorigenesis in its early stages is reviewed.
- Type
- article
- Published
- 2014-01-01
- Cited by
- 170
- References
- 110
- OpenAlex
- https://openalex.org/W24114481
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38401766
Keywords
Business, Business administration
References
- Absorption and antioxidant effects of quercetin from onions, in man
- Anti- and pro-oxidant effects of quercetin in copper-induced low density lipoprotein oxidation. Quercetin as an effective antioxidant against pro-oxidant effects of urate.
- Phytochemicals in Cancer Prevention and Therapy: Truth or Dare?
- Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases.
- Antioxidants and cancer, part 3: quercetin.
- Flavonoids as antioxidants: determination of radical-scavenging efficiencies.
- Quercetin metabolites inhibit copper ion‐induced lipid peroxidation in rat plasma 1
- Chemoprevention: an essential approach to controlling cancer
- A New Perspective on the Quercetin Paradox in Male Reproductive Dysfunction
- Anti- and pro-oxidant effects of urate in copper-induced low-density lipoprotein oxidation.
- Glycogen synthase kinase 3: more than a namesake
- Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia
- Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2).
- The antiproliferative effect of Quercetin in cancer cells is mediated via inhibition of the PI3K-Akt/PKB pathway.
- Health effects of quercetin: from antioxidant to nutraceutical.
- Inhibitory effect of a quercetin metabolite, quercetin 3-O-beta-D-glucuronide, on lipid peroxidation in liposomal membranes.
- The hormesis database: the occurrence of hormetic dose responses in the toxicological literature.
- Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles.
- The quercetin paradox.
- Activation of PI3K/Akt/IKK-α/NF-κB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin
Cited by
- Chemotherapeutic potential of quercetin on human bladder cancer cells
- Codelivery of Adriamycin and P-gp Inhibitor Quercetin Using PEGylated Liposomes to Overcome Cancer Drug Resistance.
- Chitosan nanoparticles and quercetin modulate gene expression and prevent the genotoxicity of aflatoxin B1 in rat liver
- Quercetin reduced inflammation and increased antioxidant defense in rat adjuvant arthritis.
- Quercetin regulates β‐catenin signaling and reduces the migration of triple negative breast cancer
- Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation
- Protective Effects of Quercetin Derivatives against Hydrogen Peroxide-Induced Oxidative Damage in PC-12 Cells
- Inhibition of protein kinase CK2 by quercetin enhances CD95-mediated apoptosis in a human thymus-derived T cell line
- Estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite norathyriol.
- The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis
- Cocrystals of quercetin: synthesis, characterization, and screening of biological activity
- Possible Synergistic Effect and Antioxidant Properties of Chitosan Nanoparticles and Quercetin against Carbon Tetrachloride-Induce Hepatotoxicity in Rats
- The flavonoid quercetin ameliorates Alzheimer’s disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer’s disease model mice
- The role of heat shock protein 90 in modulating ischemia–reperfusion injury in the kidney
- The pleiotropic flavonoid quercetin: from its metabolism to the inhibition of protein kinases in chronic lymphocytic leukemia.
- Potent Anti-Proliferative, Pro-Apoptotic Activity of the Maytenus Royleanus Extract against Prostate Cancer Cells: Evidence in In-Vitro and In-Vivo Models
- Cytotoxic Properties of Lyophilized Beers in a Malignant Cell Line
- Cancer-type-specific crosstalk between autophagy, necroptosis and apoptosis as a pharmacological target.
- Broad targeting of resistance to apoptosis in cancer
- Molecular Targets of Naturopathy in Cancer Research: Bridge to Modern Medicine
Related papers
No related papers recorded.