Gosha-jinki-gan reduced oxaliplatin-induced hypersensitivity to cold sensation and its effect would be related to suppression of the expression of TRPM8 and TRPA1 in rats
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Summary
Results suggest that coadministration of GJG may improve Oxp-induced cold hypersensitivity by suppressing the overexpression of TRPM8 and TRPA1 mRNA.
- Type
- article
- Published
- 2014-01-01
- Cited by
- 29
- References
- 19
- Access
- Open access
- OpenAlex
- https://openalex.org/W24052105
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28889112
Keywords
Radiological weapon, Environmental impact assessment, Environmental planning, Environmental science, Environmental resource management
References
- Gosha‐jinki‐gan reduces transmitter proteins and sensory receptors associated with C fiber activation induced by acetic acid in rat urinary bladder
- Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice
- Management of oxaliplatin-induced peripheral neuropathy
- The thermo‐TRP ion channel family: properties and therapeutic implications
- Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensation
- Efficacy of Goshajinkigan for Peripheral Neurotoxicity of Oxaliplatin in Patients with Advanced or Recurrent Colorectal Cancer
- Goshajinkigan reduces oxaliplatin-induced peripheral neuropathy without affecting anti-tumour efficacy in rodents.
- A review on oxaliplatin-induced peripheral nerve damage.
- Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain
- Spared nerve injury: an animal model of persistent peripheral neuropathic pain
- Antinociceptive effect of Gosha-jinki-gan, a Kampo medicine, in streptozotocin-induced diabetic mice.
- Effect of Gosha-jinki-gan, a Kampo medicine, on enhanced platelet aggregation in streptozotocin-induced diabetic rats.
- Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade.
- Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
- Molecular Pain
- Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice
- Preventive effect of goshajinkigan on peripheral neurotoxicity of FOLFOX therapy: a placebo-controlled double-blind randomized phase II study (the GONE Study).
- Preventive and Inhibitory Effects of Goshajinkigan with Respect to Neurotoxicity Induced by mFOLFOX6 in Colorectal Cancer Therapy
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method
Cited by
- The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action
- Low-level laser therapy alleviates mechanical and cold allodynia induced by oxaliplatin administration in rats
- Permeation, regulation and control of expression of TRP channels by trace metal ions
- Herbal medicines for the treatment of cancer chemotherapy-induced side effects
- Etude des canaux ioniques TREK 1 et HCN dans la neuropathie chimio-induite à l'oxaliplatine.
- Preventive effect of oral goshajinkigan on chronic oxaliplatin-induced hypoesthesia in rats
- Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain.
- Go-sha-jinki-Gan (GJG) ameliorates allodynia in chronic constriction injury model mice via suppression of TNF-α expression in the spinal cord
- Application of stem cell derived neuronal cells to evaluate neurotoxic chemotherapy
- Roles of Transient Receptor Potential Ankyrin 1 in Oxaliplatin-Induced Peripheral Neuropathy.
- Effect of ninjin’yoeito and ginseng extracts on oxaliplatin-induced neuropathies in mice
- Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences
- Rokumigan alleviates oxaliplatin‐induced cold hypersensitivity by suppression of transient receptor potential cation channel subfamily M member 8 and subfamily A member 1
- Transcription factor Sp4 is required for hyperalgesic state persistence
- Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats.
- Mammalian transient receptor potential TRPA1 channels: from structure to disease.
- Pathogenesis of platinum-induced peripheral neurotoxicity: Insights from preclinical studies.
- Analysis of Risk Factors for Oxaliplatin-Induced Acute Peripheral Neuropathy
- Selenium and Neurological Diseases: Focus on Peripheral Pain and TRP Channels
- Kampo Medicine for Various Aging-Related Symptoms: A Review of Geriatric Syndrome
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