PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition
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Summary
These studies suggest that targeting PTHrP expression in the tumor cells could be a potential therapeutic strategy for breast cancers, especially those with skeletal metastases.
- Type
- article
- Published
- 2013-08-21
- Cited by
- 23
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W23983616
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18194518
Keywords
Computer science
References
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Cited by
- CAPSAZEPINE ATTENUATES CANCER-INDUCED BONE PAIN BY INHIBITING GLUTAMATE RELEASE
- Role of PTHrP in Mammary Gland Development and Breast Cancer
- Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein.
- Co-expression of parathyroid hormone related protein and TGF-beta in breast cancer predicts poor survival outcome
- The Role of ΔFosB on the Pro-survival Effect of PTHrP in Goat Mammary Epithelial Cells
- Induction of Thermal and Mechanical Hypersensitivity by Parathyroid Hormone-related Peptide (PTHrP) Through Upregulation of TRPV1 Function and Trafficking
- The parathyroid hormone-related protein is secreted during the osteogenic differentiation of human dental follicle cells and inhibits the alkaline phosphatase activity and the expression of DLX3.
- Prevention of breast cancer skeletal metastases with parathyroid hormone.
- TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis
- Molecular insights into the interplay between adiposity, breast cancer and bone metastasis
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- Roles of Parathyroid Hormone-Related Protein (PTHrP) and Its Receptor (PTHR1) in Normal and Tumor Tissues: Focus on Their Roles in Osteosarcoma
- PTH/PTHrP in controlled release hydrogel enhances orthodontic tooth movement by regulating periodontal bone remodaling.
- Extracellular Vesicles from miR-148a-5p-Enriched Bone Marrow Mesenchymal Stem Cells Relieve Hepatic Fibrosis by Targeting Smad4
- A metastasis-on-a-chip approach to explore the sympathetic modulation of breast cancer bone metastasis
- Low-intensity pulsed ultrasound/nanomechanical force generators enhance osteogenesis of BMSCs through microfilaments and TRPM7
- Parathyroid hormone 1 receptor signaling mediates breast cancer metastasis to bone in mice
- Bridging the Gap in Understanding Bone Metastasis: A Multifaceted Perspective
- Design and development of in-vitro co-culture device for studying cellular crosstalk in varied tissue microenvironment.