Postintegration HIV-1 infection of cervical epithelial cells mediates contact-dependent productive infection of T cells.
Explore this paper's citation graph
Summary
It is observed that a subset of cervical epithelial cells may be actively involved in establishing a systemic HIV infection and should be a target when designing prevention strategies to protect against HIV-1 sexual transmission.
- Type
- article
- Published
- 2013-12-01
- Cited by
- 34
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W23908485
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3028626
Keywords
Validator, Computer science, Power (physics), Simulation, Embedded system
References
- Semen-derived amyloid fibrils drastically enhance HIV infection.
- Langerhans cells, macrophages and lymphocyte subsets in the cervix and vagina of rhesus macaques.
- REVIEW ARTICLE: HIV Infection in the Female Genital Tract: Discrete Influence of the Local Mucosal Microenvironment
- Retroviral Spread by Induction of Virological Synapses
- ORIGINAL ARTICLE: Quantification and Comparison of Toll‐Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract Epithelia
- Response to Neisseria gonorrhoeae by Cervicovaginal Epithelial Cells Occurs in the Absence of Toll-Like Receptor 4-Mediated Signaling1
- Productive infection of a cervical epithelial cell line with human immunodeficiency virus: implications for sexual transmission
- Detection of HIV‐1 proviral DNA in sperm from HIV‐1-infected men
- Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies
- Syndecan captures, protects, and transmits HIV to T lymphocytes.
- Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission.
- Seminal Plasma Accelerates Semen-derived Enhancer of Viral Infection (SEVI) Fibril Formation by the Prostatic Acid Phosphatase (PAP248–286) Peptide
- Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
- Modeling Sequence Evolution in Acute HIV-1 Infection
- Safety and Effectiveness of BufferGel and 0.5% PRO2000 Gel for the Prevention of HIV Infection in Women
- Preventing disease by protecting the cervix: the unexplored promise of internal vaginal barrier devices
- Perils at mucosal front lines for HIV and SIV and their hosts
- The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men
- Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI
- Quantitation of human immunodeficiency virus type 1 RNA in cell free seminal plasma: comparison of NASBA with Amplicor reverse transcription-PCR amplification and correlation with quantitative culture.
Cited by
- HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation
- Effet du liquide séminal sur l'infection par le VIH-1 dans des modèles cellulaires et tissulaires et recherche des facteurs modulateurs
- Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16.
- Interactions between HIV-1 and Mucosal Cells in the Female Reproductive Tract
- Mucosal Immunity in the Female Genital Tract, HIV/AIDS
- Role of Semen in Modulating the Female Genital Tract Microenvironment – Implications for HIV Transmission
- Infection of Female Primary Lower Genital Tract Epithelial Cells after Natural Pseudotyping of HIV-1: Possible Implications for Sexual Transmission of HIV-1
- Influence of Common Mucosal Co‐Factors on HIV Infection in the Female Genital Tract
- The Role of Sex Hormones and the Tissue Environment in Immune Protection Against HIV in the Female Reproductive Tract
- Medroxyprogesterone Acetate Regulates HIV-1 Uptake and Transcytosis but Not Replication in Primary Genital Epithelial Cells, Resulting in Enhanced T-Cell Infection.
- ENHANCEMENT OF HIV PERSISTENCE BY ADIPOSE TISSUE
- Recent progress in HIV vaccines inducing mucosal immune responses
- Human immunodeficiency virus-associated disruption of mucosal barriers and its role in HIV transmission and pathogenesis of HIV/AIDS disease
- Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses
- The use of nanotechnology: polyanionic carbosilane dendrimers and antivirals as novel preventive methods against HIV-1 and HCV
- Supramolecular combinations of humic polyanions as potent microbicides with polymodal anti-HIV-activities
- Interaction between herpesvirus entry mediator and HSV-2 glycoproteins mediates HIV-1 entry of HSV-2-infected epithelial cells.
- In vitro models for deciphering the mechanisms underlying the sexual transmission of viruses at the mucosal level.
- Target Cells for HIV-1/SIV Infection in Mucosal Tissue
- Mucosa: Key Interactions Determining Sexual Transmission of the HIV Infection