Repair of Oxidative DNA Damage and Cancer: Recent Progress in DNA Base Excision Repair
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Summary
The emphasis of this review is to highlight the importance of the cellular response to oxidative DNA damage during carcinogenesis, and the unusual activity and subcellular distribution of apurinic/apyrimidinic endonuclease 1, an essential DNA repair factor/redox sensor, affect cancer malignancy by increasing cellular resistance to oxidative stress and by positively influencing cell proliferation.
- Type
- article
- Published
- 2014-01-21
- Cited by
- 152
- References
- 191
- Access
- Open access
- OpenAlex
- https://openalex.org/W23901781
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:29120467
Keywords
Political science
References
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- Mecanismos de reparo de DNA envolvidos com lesões induzidas por agente alquilante (Nimustina) em células humanas e sua associação com a resistência de gliomas.
- OGG1 Involvement in High Glucose-Mediated Enhancement of Bupivacaine-Induced Oxidative DNA Damage in SH-SY5Y Cells
- A dual-fluorescent reporter facilitates identification of thiol compounds that suppress microsatellite instability induced by oxidative stress.
- DNA Repair Meets the RNA World
- Tumor suppressor Ing1b facilitates DNA repair and prevents oxidative stress induced cell death
- Suppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease
- Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways*
- Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
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- Synergistic Induction of Erlotinib-Mediated Apoptosis by Resveratrol in Human Non-Small-Cell Lung Cancer Cells by Down-Regulating Survivin and Up-Regulating PUMA
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- Polymorphisms within base and nucleotide excision repair pathways and risk of differentiated thyroid carcinoma.
- Adenine Glycosylase MutY of Corynebacterium pseudotuberculosis presents the antimutator phenotype and evidences of glycosylase/AP lyase activity in vitro.
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