Inhibition of endoplasmic reticulum Ca²⁺ ATPase in preBötzinger complex of neonatal rat does not affect respiratory rhythm generation.
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Summary
Results show that after inhibition of SERCA and depletion of intracellular Ca(2+) stores, respiratory rhythm remains substantially the same, suggesting that this source of Ca( 2+) does not significantly contribute to rhythm generation in the preBötC in vitro.
- Type
- article
- Published
- 2012-11-08
- Cited by
- 23
- References
- 59
- OpenAlex
- https://openalex.org/W22906476
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22414772
Keywords
Philosophy, Humanities
References
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Cited by
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- Thapsigargin-induced activation of Ca(2+)-CaMKII-ERK in brainstem contributes to substance P release and induction of emesis in the least shrew.
- Mixed-mode oscillations and population bursting in the pre-Bötzinger complex
- Substitution of extracellular Ca2+ by Sr2+ prolongs inspiratory burst in pre-Bötzinger complex inspiratory neurons.
- Role of Calcium in Vomiting: Revelations from the Least Shrew Model of Emesis
- Functional Interactions between Mammalian Respiratory Rhythmogenic and Premotor Circuitry
- Ca2+ signaling and emesis: Recent progress and new perspectives.
- Respiratory Rhythm Generation: The Whole Is Greater Than the Sum of the Parts.
- Rhythmogenic And Premotor Functions Of Dbx1 Interneurons In The Pre-Bötzinger Complex And Reticular Formation: Modeling And Simulation Studies
- Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits
- Neural mechanisms for sigh generation during prenatal development.
- Intracellular emetic signaling evoked by the L-type Ca2+ channel agonist FPL64176 in the least shrew (Cryptotis parva)
- Biophysical mechanisms in the mammalian respiratory oscillator re-examined with a new data-driven computational model
- Intracellular vomit signals and cascades downstream of emetic receptors: Evidence from the least shrew (Cryptotis parva) model of vomiting
- Mechanisms of Nausea and Vomiting: Current Knowledge and Recent Advances in Intracellular Emetic Signaling Systems
- Putting the theory into ‘burstlet theory’ with a biophysical model of burstlets and bursts in the respiratory preBötzinger complex
- Bifurcations underlying sigh and eupnea rhythmic transition in a pre-Bötzinger complex model
- RNA sequencing least shrew (Cryptotis parva) brainstem and gut transcripts following administration of a selective substance P neurokinin NK1 receptor agonist and antagonist expands genomics resources for emesis research
- A Comparative Study of the Antiemetic Effects of α2-Adrenergic Receptor Agonists Clonidine and Dexmedetomidine against Diverse Emetogens in the Least Shrew (Cryptotis parva) Model of Emesis
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