5-Methylcytosine and 5-Hydroxymethylcytosine Spatiotemporal Profiles in the Mouse Zygote
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Summary
The results support the already proposed hypothesis that 5-hydroxymethylcytosine is not a simple intermediate in an active demethylation process and could play a role of its own during early development.
- Type
- article
- Published
- 2012-05-31
- Cited by
- 73
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W22693592
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16075250
Keywords
Humanities, Political science, Art
References
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- Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote
- Dynamics of DNA‐demethylation in early mouse and rat embryos developed in vivo and in vitro
- Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints
- Role of Tet proteins in 5mC to 5hmC conversion, ES cell self-renewal, and ICM specification
- DNA methylation pattern in human zygotes and developing embryos.
- Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development
- Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
- [Embryonic genome activation].
- Regulation of transcriptional activity during the first and second cell cycles in the preimplantation mouse embryo.
- Tet1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
- Genome-wide Regulation of 5hmC, 5mC and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells
- Genome restructuring in mouse embryos during reprogramming and early development.
- Epigenetic reprogramming in mouse primordial germ cells.
- Global Mapping of DNA Methylation in Mouse Promoters Reveals Epigenetic Reprogramming of Pluripotency Genes
Cited by
- Maternal TET3 is dispensable for embryonic development but is required for neonatal growth
- An Improved Antibody-based Method to Detect Whole Genome Cytosine Methylation in Mouse Embryonic Fibroblasts
- Epigenetic regulation of genomic imprinting from germ line to preimplantation
- Epigenetics and periconception environment: an introduction.
- The epigenetics of embryo development
- Genomic imprinting in farm animals.
- Epigenetics, a key for unlocking complex CNS disorders? Therapeutic implications.
- Determinants of valid measurements of global changes in 5'-methylcytosine and 5'-hydroxymethylcytosine by immunolocalisation in the early embryo.
- Function of TET proteins in germ cell reprogramming
- DNA methylation and its role in the trophoblast cell lineage.
- Gene Expression of Dnmt1 Isoforms in Porcine Oocytes, Embryos, and Somatic Cells
- Epigenetics, embryo quality and developmental potential.
- Diversity of two forms of DNA methylation in the brain
- Oxidized form of 5-methylcytosine—5-hydroxymethylcytosine: a new insight into the biological significance in the mammalian genome
- Epigenetics in fertilization and preimplantation embryo development.
- 5-Hydroxymethylcytosine is a predominantly stable DNA modification
- 5′-methylcytosine and 5′-hydroxymethylcytosine Each Provide Epigenetic Information to the Mouse Zygote
- Current technological advances in mapping new DNA modifications
- Understanding the complexity of antigen retrieval of DNA methylation for immunofluorescence-based measurement and an approach to challenge.
- Male obesity and subfertility, is it really about increased adiposity?
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