Molecular pathology of tumor‐initiating cells: Lessons from Philadelphia chromosome‐positive leukemia
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Summary
Examination of the pathophysiology of chronic myelogenous leukemia and precursor B cell acute lymphoblastic leukemia has provided interesting insights into not only the hierarchy of leukemia stem cells but also their clonal evolution.
- Type
- article
- Published
- 2011-09-01
- Cited by
- 9
- References
- 70
- OpenAlex
- https://openalex.org/W21884299
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24238264
Keywords
Humanities, Computer science, Art
References
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- Patching the gaps in Hedgehog signalling
- Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
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- Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo.
- Identification of human brain tumour initiating cells
- FOXO transcription factors at the interface between longevity and tumor suppression
- "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells
- Epigenetic signatures of stem-cell identity
- Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice.
- Lipid signalling in disease
- Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.
- A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
- Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
- IFNα activates dormant haematopoietic stem cells in vivo
- Mechanisms of BCR–ABL in the pathogenesis of chronic myelogenous leukaemia
- Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.
Cited by
- Cancer stem cell targeting: the next generation of cancer therapy and molecular imaging.
- Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia
- Resveratrol sensitized leukemia stem cell-like KG-1a cells to cytokine-induced killer cells-mediated cytolysis through NKG2D ligands and TRAIL receptors
- Integrating current treatment options for TKI-resistant chronic myeloid leukemia.
- Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
- An overview of quinoline as a privileged scaffold in cancer drug discovery
- Tyrosine Kinase Inhibitor Treatment for Newly Diagnosed Chronic Myeloid Leukemia.
- Prediction of Response to FDA-Approved Targeted Therapy and Immunotherapy in Acute Lymphoblastic Leukemia (ALL)
- Molecular Mechanisms of CML Stem Cell Maintenance
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