Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice.
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Summary
Loganin exhibits protective effects against hepatic injury and other diabetic complications associated with abnormal metabolic states and inflammation caused by oxidative stress and advanced glycation endproduct formation.
- Type
- article
- Published
- 2010-12-01
- Cited by
- 110
- References
- 42
- OpenAlex
- https://openalex.org/W20826139
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44872426
Keywords
Medicine, Humanities, Gynecology, Philosophy
References
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- Effects of morroniside isolated from Corni Fructus on renal lipids and inflammation in type 2 diabetic mice
- Role of Sterol Regulatory Element-binding Protein 1 in Regulation of Renal Lipid Metabolism and Glomerulosclerosis in Diabetes Mellitus*
- Impact of metabolic abnormalities for beta cell function: clinical significance and underlying mechanisms.
- Protection Against Hypercholesterolemia by Corni Fructus Extract and Its Related Protective Mechanism
- Triglycerides Potentiate the Inflammatory Response in Rat Kupffer Cells
- GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.
- Lipid signalling in disease
- Nonalcoholic fatty liver disease in type 2 diabetes mellitus
- Diabetic dyslipidaemia: from basic research to clinical practice*
- A fluorometric method for determination of oxidized and reduced glutathione in tissues.
- Advanced glycation end products and the progressive course of renal disease.
- The beneficial effects of morroniside on the inflammatory response and lipid metabolism in the liver of db/db mice.
- Determination of malonaldehyde precursor in tissues by thiobarbituric acid test.
- AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept.
- Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida fruits with health benefits.
Cited by
- Physicochemical and Sensory Properties of Yogurt Supplemented with Corni fructus during Storage
- Comparative pharmacokinetics of the main compounds of Shanzhuyu extract after oral administration in normal and chronic kidney disease rats.
- Loganin protects against pancreatitis by inhibiting NF-κB activation.
- Astaxanthin and Corni Fructus Protect Against Diabetes-Induced Oxidative Stress, Inflammation, and Advanced Glycation End Product in Livers of Streptozotocin-Induced Diabetic Rats
- 추출 온도에 따른 산수유의 항산화 활성 및 항유전독성 효과 비교
- Effect of the best compatibility of components in Corni Fructus on WT1 expression in glomerular podocytes of type 2 diabetic rats with early nephropathy.
- Beneficial Effect of 7-O-Galloyl-D-sedoheptulose, a Polyphenol Isolated from Corni Fructus, against Diabetes-Induced Alterations in Kidney and Adipose Tissue of Type 2 Diabetic db/db Mice
- The protective effect of the Cornus mas fruits (cornelian cherry) on hypertriglyceridemia and atherosclerosis through PPARα activation in hypercholesterolemic rabbits.
- Inhibitory effects of corni fructus extract on angiogenesis and adipogenesis.
- An Expeditious Method Combining Multi-Components Determination and Fingerprinting Based on Ultra Performance Liquid Chromatography-Photo Diode Array-Tandem Mass Spectrometry and Chemometrics: Application for Authentication and Quality Evaluation of Cornus Officinalis Sieb. et Zucc
- Macrophage-mediated glucolipotoxicity via myeloid-related protein 8/toll-like receptor 4 signaling in diabetic nephropathy
- Hepato-protective effects of loganin, iridoid glycoside from Corni Fructus, against hyperglycemia-activated signaling pathway in liver of type 2 diabetic db/db mice.
- Anti-Inflammatory Iridoids of Botanical Origin
- Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging
- Hepatic metabolism of sulfur amino acids in db/db mice.
- Characterization of in Vitro Metabolism of Loganin by Human Intestinal Microflora Using Ultra-High Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry
- Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells.
- Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice
- Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway
- The Butanol Fraction of Guava (Psidium cattleianum Sabine) Leaf Extract Suppresses MMP-2 and MMP-9 Expression and Activity Through the Suppression of the ERK1/2 MAPK Signaling Pathway
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