Substance use disorders: realizing the promise of pharmacogenomics and personalized medicine.
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Summary
This review enumerates barriers to realizing the potential of personalized medicine for substance use disorders and identifies opportunities to overcome those barriers, which involve the development of translational approaches that focus on theDevelopment of brain-based phenotypes that serve as the target of both treatment development and of genetic research.
- Type
- dissertation
- Published
- 2010-03-24
- Cited by
- 66
- References
- 67
- OpenAlex
- https://openalex.org/W20192794
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25057624
Keywords
History
References
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Cited by
- Brain proton magnetic resonance spectroscopy of alcohol use disorders
- Adolescent psychotherapy for addiction medicine: From brain development to neurocognitive treatment mechanisms.
- Importance of construct validity in functional neuroimaging of craving.
- Effect of Homozygous Deletions at 22q13.1 on Alcohol Dependence Severity and Cue-Elicited BOLD Response in the Precuneus
- The Contributions of Cognitive Neuroscience and Neuroimaging to Understanding Mechanisms of Behavior Change in Addiction
- Developing Neurobiological Endophenotypes that Reflect Failure to Control Alcohol Consumption and Dependence
- Anticipating possible policy uses of addiction neuroscience research
- Preliminary functional MRI results from a combined stop-signal alcohol-cue task.
- Brain regions affected by impaired control modulate responses to alcohol and smoking cues.
- Working memory as a moderator of impulsivity and alcohol involvement: Testing the cognitive-motivational theory of alcohol use with prospective and working memory updating data
- Brain-Based Origins of Change Language: A Beginning
- Functional connectivity and cannabis use in high-risk adolescents
- Proposed model of the neurobiological mechanisms underlying psychosocial alcohol interventions: the example of motivational interviewing.
- White matter integrity is associated with alcohol cue reactivity in heavy drinkers
- Interactive Effects of Chronic Cigarette Smoking and Age on Hippocampal Volumes
- Maximizing Effectiveness Trials in PTSD and SUD Through Secondary Analysis: Benefits and Limitations Using the National Institute on Drug Abuse Clinical Trials Network “Women and Trauma” Study as a Case Example
- Neuroimaging mechanisms of change in psychotherapy for addictive behaviors: Emerging translational approaches that bridge biology and behavior
- Perceptions of Genetic Testing and Genomic Medicine among Drug Users
- Impulsivity, variation in the cannabinoid receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes, and marijuana-related problems.
- Neuroimaging in clinical studies of craving: importance of reward and control networks.
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