Cathepsins are required for Toll-like receptor 9 responses.

Keywords

Geography

References

• A human homologue of the Drosophila Toll protein signals activation of adaptive immunityRuslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway — 1997
• Regulatory Roles for MD-2 and TLR4 in Ligand-Induced Receptor Clustering1Makiko Kobayashi, Shin-ichiroh Saitoh, Natsuko Tanimura — 2006
• Cysteine cathepsins in the immune response.Tina Zavašnik‐Bergant, Boris Turk — 2006
• Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptorsElizabeth A. Leadbetter, Ian R. Rifkin, Andreas M. Hohlbaum — 2002
• Lysosomal cysteine proteases (cathepsins): promising drug targets.Dušan Turk, Gregor Gunčar — 2003
• Lysosomal cysteine proteases regulate antigen presentationKaren Honey, Alexander Y. Rudensky — 2003
• A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.Stanimir S. Ivanov, Ana‐Maria Dragoi, Xin Wang — 2007
• Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4Masahiro Yamamoto, Shintaro Sato, Hiroaki Hemmi — 2002
• CD36 is a sensor of diacylglyceridesKasper Hoebe, Philippe Georgel, Sophie Rutschmann — 2005
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• Crystal Structures of Human MD-2 and Its Complex with Antiendotoxic Lipid IVaUmeharu Ohto, Koichi Fukase, Kensuke Miyake — 2007
• TLR9 signals after translocating from the ER to CpG DNA in the lysosomeEicke Latz, Annett Schoenemeyer, Alberto Visintin — 2004
• Toll-like receptors.Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira — 2003
• Role of the Heat Shock Protein 90 in Immune Response Stimulation by Bacterial DNA and Synthetic OligonucleotidesFu‐Gang Zhu, David S. Pisetsky — 2001
• Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.Mi Sun Jin, Sung Eun Kim, Jin Young Heo — 2007
• Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran.Ho Min Kim, Beom Seok Park, Jung-In Kim — 2007
• Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEJane Tian, Ana M. Avalos, Su-Yau Mao — 2007
• Innate immune recognition.Charles A. Janeway, Ruslan Medzhitov — 2002
• Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cyclingWera Roth, Jan M. Deussing, Vladimir A. Botchkarev — 2000

Cited by

• Viral and cellular modulation of virus-induced apoptosis in experimental infection modelsPiritta Peri — 2010
• Toll-like receptor 9 and Systemic Lupus Erythromatosus: novel insightsArie Jan Stoppelenburg — 2009
• Rôle de l'ADN dans l'activation du TLR9 lors de l'infection par Leishmania major : propriétés des séquences génomiques et implication des facteurs protéiquesMélissa Erin Khan — 2014
• Identification, mRNA expression profiling and activity characterization of cathepsin L from red drum (Sciaenops ocellatus)Bo-guang Sun, Yonghua Hu — 2015
• Transcriptomic and proteomic analysis of arbovirus-infected tick cellsSabine Weisheit — 2014
• Vergleich der TLR9-abhängigen Aktivierung von Transkriptionsfaktoren in intestinalen Immunzellen unter gesunden und chronisch entzündlichen BedingungenS. Siller — 2015
• Invariant chain is a new chaperone for TLR7 in B cells.Mira Tohmé, Bénédicte Manoury — 2015
• Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microgliaRicha Hanamsagar, Victor J. Torres, Tammy Kielian — 2011
• Immunosuppressive and antiproteolytic therapy in vascular diseasesLi-Yu Bai — 2010
• Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10–Producing B Cells in Response to Staphylococcus aureusMarijo Parčina, María Auxiliadora Miranda‐García, Sibel Durlanik — 2013
• Size-Dependent Attenuation of TLR9 Signaling by Gold Nanoparticles in MacrophagesChiau-Yuang Tsai, Shiou-Ling Lu, Chia-Wen Hu — 2012
• Receptores similares a Toll en peces: el inicio de la divergenciaIS Rondón-Barragán — 2009
• Deciphering the function of nucleic acid sensing TLRs one regulatory step at a timeR. Marek Lorri — 2011
• Cathepsin S of Sciaenops ocellatus: Identification, transcriptional expression and enzymatic activity.Bo-guang Sun, Heng Chi — 2016
• TLR9 regulation by proteolysis: A friend or a foeBénédicte Manoury — 2011
• A cell biological view of Toll-like receptor function: regulation through compartmentalizationGregory M. Barton, Jonathan C. Kagan — 2009
• Edwardsiella tarda-regulated proteins in Japanese flounder (Paralichthys olivaceus): Identification and evaluation of antibacterial potentials.Jingjing Wang, Li Sun — 2015
• Sustained activation of toll-like receptor 9 induces an invasive phenotype in lung fibroblasts: possible implications in idiopathic pulmonary fibrosis.Varvara Kirillov, Jonathan Siler, Mahalakshmi Ramadass — 2015
• Dengue Virus Infection of the Aedes aegypti Salivary Gland and Chemosensory Apparatus Induces Genes that Modulate Infection and Blood-Feeding BehaviorShuzhen Sim, José L. Ramírez, George Dimopoulos — 2012
• Asparagine Endopeptidase Controls Anti-Influenza Virus Immune Responses through TLR7 ActivationSophia Maschalidi, Signe Hässler, Fany Blanc — 2012

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