Predicting Human Hepatic Clearance Using Hypernet Neural Networks

Keywords

In vivo, Human liver, Artificial neural network, Computer science, Set (abstract data type)

References

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• Systems modeling: a pathway to drug discovery.Priyamvada Rajasethupathy, Sharat J. Vayttaden, Upinder S. Bhalla — 2005
• Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance.J. Brian Houston — 1994
• EVALUATION OF FRESH AND CRYOPRESERVED HEPATOCYTES AS IN VITRO DRUG METABOLISM TOOLS FOR THE PREDICTION OF METABOLIC CLEARANCEDermot F. McGinnity, Matthew G. Soars, Richard A. Urbanowicz — 2004
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• Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices.J. Brian Houston, David Carlile — 1997

Cited by

• Moving beyond in silico tools to in silico science in support of drug development researchC. Anthony Hunt, Glen E. P. Ropella — 2011

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