Calcium-mediated activation of PI3K and p53 leads to apoptosis in thyroid carcinoma cells
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Summary
It is suggested that apoptosis induced by cadmium in FRO cells was initiated by the rapid elevation of intracellular calcium, followed by calcium-mediated activation of PI3K/Akt and mitochondrial impairment.
- Type
- article
- Published
- 2007-05-18
- Cited by
- 52
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W17514353
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2871385
Keywords
Business
References
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Cited by
- Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway
- Indução de estresse de retículo endoplasmático como estratégia de quimiossensibilização de melanoma
- Cadmium-induced autophagy promotes survival of rat cerebral cortical neurons by activating class III phosphoinositide 3-kinase/beclin-1/B-cell lymphoma 2 signaling pathways.
- CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death
- Urotensin-II as an angiogenic factor.
- ACh Receptors Link Two Signaling Pathways to Neuroprotection against Glutamate-Induced Excitotoxicity in Isolated RGCs
- Isradipine prevents rotenone-induced intracellular calcium rise that accelerates senescence in human neuroblastoma SH-SY5Y cells.
- The role of SIRT1/AKT/ERK pathway in ultraviolet B induced damage on human retinal pigment epithelial cells.
- 2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) Induces Apoptosis via Modulating E7 Expression and Inhibition of PI3K/Akt Pathway in SiHa Human Cervical Cancer Cells
- Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network
- New insights into the Ca2+-ATPases that contribute to cadmium tolerance in yeast.
- Alpha-synuclein knockdown attenuates MPP+ induced mitochondrial dysfunction of SH-SY5Y cells.
- Phosphoinositide 3-kinase inhibitors protect mouse kidney cells from cyclosporine-induced cell death.
- Pathway of Programmed Cell Death and Oxidative Stress Induced by β-Hydroxybutyrate in Dairy Cow Abomasum Smooth Muscle Cells and in Mouse Gastric Smooth Muscle
- β2-Integrin-Mediated Adhesion and Intracellular Ca2+ Release in Human Eosinophils
- The pro-angiogenic activity of urotensin-II on human vascular endothelial cells involves ERK1/2 and PI3K signaling pathways.
- Inhibitory effect of ETB receptor on Na+–K+ ATPase activity by extracellular Ca2+ entry and Ca2+ release from the endoplasmic reticulum in renal proximal tubule cells
- Induction of cytoprotective autophagy in PC-12 cells by cadmium.
- Neurotoxicity of cadmium on immature hippocampus and a neuroprotective role for p38 MAPK.
- Effect of Mechanochemical Treatment on Physicochemical and Antitumor Properties of Betulin Diacetate Mixtures with Arabinogalactan
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