Positive-feedback loops as a flexible biological module.
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Summary
In the presence of feedback, transient induction with high pheromone levels caused persistent pathway activation, whereas at lower levels a fraction of cells became persistently active but the rest inactivated completely.
- Type
- article
- Published
- 2007-04-17
- Cited by
- 113
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W17398098
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15674870
Keywords
Geothermal gradient, Groundwater recharge, Hydrogen ion, Chemistry, Hydrology (agriculture)
References
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- Additional modules for versatile and economical PCR‐based gene deletion and modification in Saccharomyces cerevisiae
- Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase.
- Bistable expression of WOR1, a master regulator of white–opaque switching in Candida albicans
- Multistationarity, the basis of cell differentiation and memory. I. Structural conditions of multistationarity and other nontrivial behavior.
- Prediction and measurement of an autoregulatory genetic module
- Graded positional information: interpretation for both fate and guidance.
- Enhancement of cellular memory by reducing stochastic transitions
- Topology and Robustness in the Drosophila Segment Polarity Network
- ENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON.
- The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes.
- Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion
- The logical analysis of continuous, non-linear biochemical control networks.
- Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2
- Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments
- Multistability in the lactose utilization network of Escherichia coli
- Epigenetic properties of white–opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback loop
Cited by
- AUTO-INDUCTION OF GREEN FLUORESCENT PROTEIN USING THE ARA OPERON IN HIGH CELL DENSITY FERMENTATION
- Engineering of artificial cellular circuits based on the LuxI-LuxR quorum-sensing system
- Plasma Membrane Localization of Signaling Proteins in Yeast: a Dissertation
- Functional dissection of T. brucei Protein Tyrosine Phosphatase 1 and investigation of its development as a therapeutic target
- Customized Signaling Circuits
- A fungicide-responsive kinase as a tool for synthetic cell fate regulation
- A Study Of Small Gene Regulatory Networks: Robustness, Dynamics, And Behavior
- The development of RNA-based control systems to regulate signaling and dictate cell fate in a model MAPK pathway
- Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer
- Classification of Genes and Putative Biomarker Identification Using Distribution Metrics on Expression Profiles
- Comparative Functional Genomics of Stress Responses in Yeasts
- A Critical Quantity for Noise Attenuation in Feedback Systems
- Tuning the Activation Threshold of a Kinase Network by Nested Feedback Loops
- The Regulation of Filamentous Growth in Yeast
- Structure and properties of transcriptional networks driving selenite stress response in yeasts
- Some nonlinear challenges in biology
- Systems Biology: A Switch for Sex
- Transcriptional Autoregulatory Loops Are Highly Conserved in Vertebrate Evolution
- Quorum-sensing linked RNA interference for dynamic metabolic pathway control in Saccharomyces cerevisiae.
- Synthetic biosensing systems.
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