Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases
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Summary
It is proposed that the Last Universal Common Ancestor of all extant organisms contained at least three SPOUT members, ancestors of contemporary RNA MTases that carry out m1G, m3U, and 2'O-ribose methylation, respectively.
- Type
- article
- Published
- 2007-03-05
- Cited by
- 180
- References
- 113
- Access
- Open access
- OpenAlex
- https://openalex.org/W17338813
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18642532
Keywords
Humanities, Philosophy
References
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- Can correct protein models be identified?
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- Insights into catalysis by a knotted TrmD tRNA methyltransferase.
- Novel Predicted RNA-Binding Domains Associated with the Translation Machinery
- Prediction of a common fold for all four subunits of the yeast tRNA splicing endonuclease: implications for the evolution of the EndA/Sen family
- Fold change in evolution of protein structures.
- m5C RNA and m5C DNA methyl transferases use different cysteine residues as catalysts.
- Circular Permutations in the Molecular Evolution of DNA Methyltransferases
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- New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA
- Structures and folding pathways of topologically knotted proteins
- Staphylococcal cassette chromosome mec (SCCmec) and characterization of the attachment site (attB) of methicillin resistant Staphylococcus aureus (MRSA) and methicillin susceptible Staphylococcus aureus (MSSA) isolates.
- A TALE OF TWO METHYLATION MODIFICATIONS IN ARCHAEAL RNAs
- Development and validation of a novel method for clustering protein sequences and detecting diagnostic motifs
- DYNAMICS OF SUBSTRATE INTERACTIONS IN tRNA (m1G37) METHYLTRANSFERASE: IMPLICATIONS FOR DRUG DISCOVERY
- Heterogeneous side chain conformation highlights a network of interactions implicated in hysteresis of the knotted protein, Minimal Tied Trefoil (MTTTm)
- Etudes structurales de différents processus biologiques impliquant les ARN de transfert
- The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics
- Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2′-O-methyltransferase
- Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by Comparative Transcriptome Analyses
- Structural insights into radical generation by the radical SAM superfamily.
- Diversity in mechanism and function of tRNA methyltransferases
- Genes and proteins involved in RNA modification: evolutionary genomic context and characterization of YibK and GidB Methyltransferases
- Functional Roles in S-Adenosyl-L-Methionine Binding and Catalysis for Active Site Residues of the Thiostrepton Resistance Methyltransferase
- tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily
- Enzymology of tRNA modification in the bacterial MnmEG pathway.
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