TRPP2 channel regulation.
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Summary
The reader is introduced to the field of cystic kidney diseases and to the PKD2 gene, before the ion channel properties of polycystin-2 are discussed in great detail.
- Type
- article
- Published
- 2007-01-01
- Cited by
- 24
- References
- 75
- OpenAlex
- https://openalex.org/W17217069
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38930445
Keywords
Philosophy
References
- Voltage Dependence and pH Regulation of Human Polycystin-2-mediated Cation Channel Activity*
- Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
- Cytoskeletal regulation of calcium‐permeable cation channels in the human syncytiotrophoblast: role of gelsolin
- The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium.
- Cloning of inv, a gene that controls left/right asymmetry and kidney development
- The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination.
- Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor.
- Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2.
- Two populations of node monocilia initiate left-right asymmetry in the mouse.
- A study of genetic linkage heterogeneity in 35 adult-onset polycystic kidney disease families
- A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans
- Cloning and characterization of the murine pkd2 promoter.
- Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease.
- Autosomal dominant polycystic kidney disease in Toronto.
- Polycystin-L is a calcium-regulated cation channel permeable to calcium ions
- Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates.
- PKD2, a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
- Location of mutations within the PKD2 gene influences clinical outcome.
- The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway.
- The isolated C-terminus of polycystin-1 promotes increased ATP-stimulated chloride secretion in a collecting duct cell line.
Cited by
- Strukturelle und biochemische Charakterisierung des cytosolischen C-Terminus von Polycystin-2 und seine Interaktion mit dem Zytoskelett-assoziierten Protein mammalian diaphanous homolog 1
- TRPC channels in human mast cells
- THE CONCISE GUIDE TO PHARMACOLOGY 2013/14:ION CHANNELS
- Polycystins and cellular Ca2+ signaling
- Ca2+ Channels on the Move
- Macromolecular assembly of polycystin-2 intracytosolic C-terminal domain
- Mechanosensitive TRP channels in cardiovascular pathophysiology.
- Feedback mechanisms in the regulation of intracellular calcium ([Ca2+]i) in the peripheral nociceptive system: role of TRPV-1 and pain related receptors.
- A method for measuring electrical signals in a primary cilium
- The human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-termini.
- Ca2+-dependent Conformational Changes in a C-terminal Cytosolic Domain of Polycystin-2*
- CATALYTIC RECEPTORS
- ION CHANNELS
- The native TRPP2-dependent channel of murine renal primary cilia.
- G PROTEIN‐COUPLED RECEPTORS
- ION CHANNELS
- Transient Receptor Potential channels (TRP) in GtoPdb v.2022.1
- ENZYMES
- TRANSPORTERS
- Transient Receptor Potential channels (TRP) in GtoPdb v.2023.2
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