Ciclesonide Disposition and Metabolism: Pharmacokinetics, Metabolism, and Excretion in the Mouse, Rat, Rabbit, and Dog
Explore this paper's citation graph
Summary
Comparisons of in vitro and in vivo metabolite profiles between mice, rats, rabbits, and dogs with those from humans indicated that metabolic pathways for ciclesonide were qualitatively similar in humans and in the 4 animal species.
- Type
- article
- Published
- 2006-11-01
- Cited by
- 8
- References
- 18
- Access
- Open access
- OpenAlex
- https://openalex.org/W17122529
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33341137
Keywords
Political science
References
- Physiological Parameters in Laboratory Animals and Humans
- Absolute Oral Versus Inhaled Bioavailability: Significance for Inhaled Drugs with Special Reference to Inhaled Glucocorticoids
- A dose-dependent effect of the novel inhaled corticosteroid ciclesonide on airway responsiveness to adenosine-5'-monophosphate in asthmatic patients.
- Effect of inhaled ciclesonide on airway responsiveness to inhaled AMP, the composition of induced sputum and exhaled nitric oxide in patients with mild asthma.
- Pharmacokinetics of [14C]Ciclesonide After Oral and Intravenous Administration to Healthy Subjects
- Treatment of asthma by the inhaled corticosteroid ciclesonide given either in the morning or evening.
- Drug Treatment of Airway Inflammation in Asthma
- Circadian rhythm of serum cortisol after repeated inhalation of the new topical steroid ciclesonide.
- Population Pharmacokinetics and Pharmacodynamics of Ciclesonide
- Inhaled glucocorticoids for asthma.
Cited by
- Tissue Accumulation Kinetics of Ciclesonide‐active Metabolite and Budesonide in Mice
- Comparative In Vitro Metabolism of 14C-Ciclesonide in Hepatocytes From the Mouse, Rat, Rabbit, Dog, and Human
- Allometric Modeling of Ciclesonide, a Nonhalogenated Glucocorticoid, and Its Active Metabolite, Desisobutyrylciclesonide, Using Animal-Derived Pharmacokinetic Parameters
- Clinical Pharmacokinetic and Pharmacodynamic Profile of Inhaled Ciclesonide
- Simultaneous determination of ciclesonide and its active metabolite desisobutyryl-ciclesonide in human plasma by LC-APCI-MS/MS: application to pharmacokinetic study in healthy Chinese volunteers.
- INHALED CORTICOSTEROIDS IN PERSONS WITH HIV INFECTION: NOT THAT HARMLESS.
- Quantitative Assessment of Pulmonary Targeting of Inhaled Corticosteroids Using Ex Vivo Receptor Binding Studies
- Pharmacokinetics for Medicinal Chemists
Related papers
No related papers recorded.