Innate immune recognition and suppression of tumors.
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Summary
The strong evidence that now supports the existence of an effective cancer immune surveillance process that prevents cancer development in both mice and humans is summarized.
- Type
- article
- Published
- 2006-01-01
- Cited by
- 75
- References
- 173
- OpenAlex
- https://openalex.org/W16860661
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11123070
Keywords
Adjunct, Workforce, Transformational leadership, Leadership style, Psychology
References
- Decreased tumor surveillance in perforin-deficient mice
- Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
- The Bcl-2 family: roles in cell survival and oncogenesis
- Activation of NK cell cytotoxicity.
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- Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 41
- Cancer immunology: the search for specificity--G. H. A. Clowes Memorial lecture.
- The intriguing role of polymorphonuclear neutrophils in antitumor reactions.
- Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.
- Increased Susceptibility to Tumor Initiation and Metastasis in TNF-Related Apoptosis-Inducing Ligand-Deficient Mice1
- Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
- CD4+CD25+ suppressor T cells: more questions than answers
- NKT cells and tumor immunity—a double-edged sword
- Angiogenesis in cancer and other diseases
- Progress in human tumour immunology and immunotherapy
- Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
- Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages
- IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
- The Anti-Tumor Activity of IL-12: Mechanisms of Innate Immunity That Are Model and Dose Dependent1
- A Role for IFN-γ in Primary and Secondary Immunity Generated by NK Cell-Sensitive Tumor-Expressing CD80 In Vivo1
Cited by
- Natürliche Killerzellen in der Leukämie- und Tumortherapie
- In vitro determination and functional maturation of natural killer cells from umbilical cord blood progenitor cells
- Target Cell Topography and Cytoskeletal Reorganization in Natural Killer Cell Activity
- Development and validation of an in vitro model of dendritic cell identification and activation
- Naïve mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules
- Targeting NKG2D in tumor surveillance
- NK cells and cancer immunosurveillance
- Immunotherapy in gliomas: limitations and potential of natural killer (NK) cell therapy.
- Intracellular application of TNF-alpha impairs cell to cell communication via gap junctions in glioma cells
- A pilot study of allogeneic cellular therapy for patients with advanced hematologic malignancies.
- Otimização de metodologia para o estudo de genes KIR
- Expression Analysis of the Ligands for the Natural Killer Cell Receptors NKp30 and NKp44
- Liver natural killer cell inoculum for liver transplantation with hepatocellular carcinoma
- The role of innate immunity in spontaneous regression of cancer.
- Tumor-associated macrophages in the prospect of development of targeted anticancer
- MiRNAs Which Target CD3 Subunits Could Be Potential Biomarkers for Cancers
- T cell immunoglobulin domain and mucin domain-3 as an emerging target for immunotherapy in cancer management
- Immune Signatures of Murine and Human Cancers Reveal Unique Mechanisms of Tumor Escape and New Targets for Cancer Immunotherapy
- Germ-line mutations, pancreatic inflammation, and pancreatic cancer.
- Impaired tumor rejection by memory CD8 T cells in mice with NKG2D dysfunction
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