Short RNAs repress translation after initiation in mammalian cells.
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Summary
Results suggest that repression by short RNAs, and thus probably miRNAs, is primarily due to ribosome drop off during elongation of translation.
- Type
- article
- Published
- 2006-02-17
- Cited by
- 855
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W16483934
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37561446
Keywords
Economics
References
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- Impaired Control of IRES-Mediated Translation in X-Linked Dyskeratosis Congenita
- Human let-7a miRNA blocks protein production on actively translating polyribosomes
- Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation
- Translational Medicine: microRNAs: a new emerging class of players for disease diagnostics and gene therapy
- Inhibition of HCV replication by small interfering RNA.
- MicroRNAs in breast cancer
- MicroRNA-regulated transgene expression systems for gene therapy and virotherapy.
- Structural and quantitative proteomic analyses of argonaute2-containing ribonucleoprotein complexes
- Role of miRNAs in CD4 T cell plasticity during inflammation and tolerance
- CryomiRs: towards the identification of a cold-associated family of microRNAs.
- Therapeutic Targeting of microRNAs in Cancer: Future Perspectives
- Circulating and urinary microRNAs as possible biomarkers in kidney transplantation.
- Translational control of endogenous microRNA target genes in C. elegans.
- RNA Interference by the Numbers: Explaining Biology Through Enzymology: A Dissertation
- Novel Bioinformatics Approaches for MicroRNA Detection and Target Prediction.
- Understanding how miRNAs post-transcriptionally regulate gene expression.
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