Noncanonical functions of BCL-2 proteins in the nervous system.
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Summary
Analysis of BCL-2 family functions in the nervous system has revealed unexpected outcomes that can serve to further stimulate critical probing of the yet unknown biochemical functions of B CL-2 proteins.
- Type
- review
- Published
- 2010-01-01
- Cited by
- 7
- References
- 139
- OpenAlex
- https://openalex.org/W16068352
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30412405
Keywords
Programmed cell death, Cell biology, Phenotype, Mitochondrion, Biology
References
- Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
- Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene
- Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery.
- Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling.
- Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets
- Sindbis virus vector system for functional analysis of apoptosis regulators.
- Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.
- Neuronal apoptosis pathways in Sindbis virus encephalitis.
- Inhibition of virus-induced neuronal apoptosis by Bax
- Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
- Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence
- Loss of the p53 tumor suppressor gene protects neurons from kainate- induced cell death
- c‐yes and bc1‐2 genes located on 18q21.3 in a follicular lymphoma cell line carrying a t(14;18) chromosomal translocation
- The Bcl-2 protein family: arbiters of cell survival.
- Perspective: virus infections and the death of neurons.
- Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands
- Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins.
- Aven-dependent activation of ATM following DNA damage.
- Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.
- Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics.
Cited by
- Multipolar functions of BCL-2 proteins link energetics to apoptosis
- Cell Signaling Underlying Epileptic Behavior
- Role and Treatment of Mitochondrial DNA-Related Mitochondrial Dysfunction in Sporadic Neurodegenerative Diseases
- Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts
- Antitumor activity of total paeony glycoside against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo
- Intermediate progenitors are increased by lengthening of the cell cycle through calcium signaling and p53 expression in human neural progenitors
- Molecular mechanisms controlling neuronal Bak expression
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