Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

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Summary

Activity was markedly decreased by using the Nedd8-unmodified mutant cullin-1 (K696R), indicating that the modification may play an important role on the SCF(skp2) activity toward p27(kip1), one of the components of SCF.

Type
dissertation
Published
2000-04-21
Cited by
138
References
17
Access
Open access

Keywords

Carnot cycle, Refrigeration, Refrigerant, Process engineering, Process (computing)

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