Myosin light chain phosphorylation‐dependent modulation of volume‐regulated anion channels in macrovascular endothelium
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Summary
Analysis of the effects of inhibitors of myosin light chain kinase (MLCK) or MLCP on VRAC in CPAE indicates that activation of VRAC is modulated by MLC phosphorylation.
- Type
- article
- Published
- 2000-01-28
- Cited by
- 42
- References
- 35
- OpenAlex
- https://openalex.org/W10682857
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1400692
Keywords
Philosophy
References
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- Involvement of PKC‐α in regulatory volume decrease responses and activation of volume‐sensitive chloride channels in human cervical cancer HT‐3 cells
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- Activation of protein kinase Cα couples cell volume to membrane Cl− permeability in HTC hepatoma and Mz‐ChA‐1 cholangiocarcinoma cells
- A Serine Residue in ClC-3 Links Phosphorylation–Dephosphorylation to Chloride Channel Regulation by Cell Volume
- Thrombin Inactivates Myosin Light Chain Phosphatase via Rho and Its Target Rho Kinase in Human Endothelial Cells*
- Molecular Determinants of Nuclear Protein Phosphatase-1 Regulation by NIPP-1*
- Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels.
- Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1
- Regulation of a swelling‐activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins
- Activation of the volume-sensitive chloride current in vascular endothelial cells requires a permissive intracellular Ca
Cited by
- Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin.
- Preliminary research on myosin light chain kinase in rabbit liver.
- Sensors and signal transduction pathways in vertebrate cell volume regulation.
- Cell volume homeostatic mechanisms: effectors and signalling pathways
- Activation of kinases upon volume changes: role in cellular homeostasis.
- Actomyosin is involved in the plasmolytic cycle: gliding movement of the deplasmolyzing protoplast
- Peroxynitrite enhances astrocytic volume‐sensitive excitatory amino acid release via a src tyrosine kinase‐dependent mechanism
- Cellular function and control of volume-regulated anion channels
- The cytoskeleton and cell volume regulation.
- Hydrogen Peroxide Potentiates Volume-sensitive Excitatory Amino Acid Release via a Mechanism Involving Ca2+/Calmodulin-dependent Protein Kinase II*
- Swelling‐activated ion channels: functional regulation in cell‐swelling, proliferation and apoptosis
- Amino Acid Osmolytes in Regulatory Volume Decrease and Isovolumetric Regulation in Brain Cells: Contribution and Mechanisms
- Regulation of the Cellular Content of the Organic Osmolyte Taurine in Mammalian Cells
- Possible interrelationship between changes in F-actin and myosin II, protein phosphorylation, and cell volume regulation in Ehrlich ascites tumor cells.
- Hypotonicity induces membrane protrusions and actin remodeling via activation of small GTPases Rac and Cdc42 in Rat-1 fibroblasts.
- Ion channels and transporters involved in cell volume regulation and sensor mechanisms
- Structure and pharmacology of swelling‐sensitive chloride channels, ICl,swell
- Myosin light chain kinase modulates hypotonicity-induced Ca2+ entry and Cl– channel activity in human cervical cancer cells
- Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts
- Intracellular Signalling Involved in Volume Regulatory Decrease
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