Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission
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Summary
It was found that chromosomal abnormalities occurred rather frequently in ES cells, and this realization allowed us to select, based upon ES cell clone morphology, those clones with the highest probability of contributing to the germ line.
- Type
- article
- Published
- 1997-05-01
- Cited by
- 209
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W9142498
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18936209
Keywords
Computer science
References
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- “Chromosome Memory” of Parental Genomes in Embryonic Hybrid Cells
- BG01V: A variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation
- PRESERVATION OF GENOMIC INTEGRITY IN MOUSE EMBRYONIC STEM CELLS
- Germline modification using mouse spermatogonial stem cells.
- Experimente zur Generierung einer knockout Maus für Untersuchungen zur Funktion des Plasmodium chabaudi induzierbaren imap38 Gens
- Gene Knockout Protocols
- Nuclear Reprogramming and Stem Cells
- Distinct transcriptional signatures of aneuploidy in murine pluripotent cell populations
- The cell biology of stem cells
- CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells
- Transgenesis Techniques
- Notch signalling pathway in murine embryonic stem cell derived haematopoiesis
- The support of undifferentiated human embryonic stem cell lines by different matrices
- Experimental approaches to establish rat embryonic stem cells
- ELUCIDATING THE ROLE OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEIN 2 IN THE PATHOGENESIS OF TYPE 2 DIABETES
- The tumorigenicity of human embryonic stem cells.
- Trisomy 8 does not affect differentiative potential in a murine parthenogenetic embryonic stem cell line.
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