Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission

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Summary

It was found that chromosomal abnormalities occurred rather frequently in ES cells, and this realization allowed us to select, based upon ES cell clone morphology, those clones with the highest probability of contributing to the germ line.

Type
article
Published
1997-05-01
Cited by
209
References
33
Access
Open access

Keywords

Computer science

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