Near-infrared enzyme-activated fluorescent phospholipids for molecular imaging
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Summary
Criteria have been explored here for the first enzyme-activated fluorescent phospholipid to be synthesized by the group, Pyro-PL-BHQ, which is highly specific to phosphatidylcholine-specificospholipase C (PC-PLC), responsible for catabolizing phosphatidocholine directly to phosphocholine (PC).
- Type
- article
- Published
- 2009-01-01
- Cited by
- 0
- References
- 140
- Access
- Open access
- OpenAlex
- https://openalex.org/W7346429
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:92804533
Keywords
Phosphocholine, Phosphatidylcholine, In vivo, Phospholipase C, Phospholipid
References
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- Kinetic analysis of phospholipase A2 activity toward mixed micelles and its implications for the study of lipolytic enzymes.
- Insertion of fluorescent phospholipids into the plasma membrane of a mammalian cell.
- In vivo molecular target assessment of matrix metalloproteinase inhibition
- Detection of phosphatidylcholine-specific phospholipase C in NIH-3T3 fibroblasts and their H-ras transformants: NMR and immunochemical studies.
- Pyruvate utilization, phosphocholine and adenosine triphosphate (ATP) are markers of human breast tumor progression: a 31P- and 13C-nuclear magnetic resonance (NMR) spectroscopy study.
- Phosphorylation, transbilayer movement, and facilitated intracellular transport of diacylglycerol are involved in the uptake of a fluorescent analog of phosphatidic acid by cultured fibroblasts.
- Metabolic markers of breast cancer: enhanced choline metabolism and reduced choline-ether-phospholipid synthesis.
- Magnetic resonance spectroscopy of tumors and potential in vivo clinical applications: a review.
- Fibrin gel investment associated with line 1 and line 10 solid tumor growth, angiogenesis, and fibroplasia in guinea pigs. Role of cellular immunity, myofibroblasts, microvascular damage, and infarction in line 1 tumor regression.
- Nuclear magnetic resonance spectroscopy of cancer.
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