Enhancement of experimental metastasis by pretreatment of tumour cells with hydroxyurea
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Summary
The results obtained suggest that the chemotherapeutic agent HU may facilitate tumour progression via a direct action on neoplastic cells through enhancement of tumour‐cell arrest.
- Type
- article
- Published
- 1986-07-15
- Cited by
- 24
- References
- 35
- OpenAlex
- https://openalex.org/W3721624
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:29953398
Keywords
Computer science
References
- The experimental study of tumor progression: a review.
- Enhancement of experimental lung metastases by cultured B16 melanoma cells treated with (+/-)-1,2-bis(3,5-dioxopiperazin-1-y)propane (ICRF-159).
- Induction of morphological transformation in mouse C3H/10T1/2 clone 8 cells and chromosomal damage in hamster A(T1)C1-3 cells by cancer chemotherapeutic agents.
- Mutagenicity of cancer chemotherapeutic agents in the Salmonella/microsome test.
- Tumorigenicity in vivo and induction of malignant transformation and mutagenesis in cell cultures by adriamycin and daunomycin.
- Metastatic heterogeneity of cells from an ultraviolet light-induced murine fibrosarcoma of recent origin.
- Mutagenic responses of thirteen anticancer drugs on mutation induction at multiple genetic loci and on sister chromatid exchanges in Chinese hamster ovary cells.
- Errors in DNA replication as a basis of malignant changes.
- UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells
- Mutation selection and the natural history of cancer
- Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea
- Selection of successive tumour lines for metastasis.
- The clonal evolution of tumor cell populations.
- Gradual transformation of solid into ascites tumors; evidence favoring the mutation-selection theory.
- Relevance of density, size and DNA content of tumour cells to the lung colony assay.
- Platinum(II) complexes generate frame-shift mutations in test strains of Salmonella typhimurium.
- Fifth Gordon Hamilton-Fairley memorial lecture. Methotrexate resistance and gene amplification: an experimental model for the generation of cellular heterogeneity.
- The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis.
- Enhancement by cytotoxic agents of artificial pulmonary metastasis.
- Metastasis of a transplantable mammary tumour in rats treated with cyclophosphamide and/or irradiation.
Cited by
- Induction of heat shock protein 27 by hydroxyurea and its relationship to experimental metastasis
- Heritable high frequency modulation of antigen expression in neoplastic cells exposed to 5-aza-2'-deoxycytidine or hydroxyurea: analysis and implications.
- Effects of folate deficiency on the metastatic potential of murine melanoma cells.
- The role of DNA methylation in cancer.
- The effectiveness of cis-platinum, cyclophosphamide and melphalan in treating disseminated tumor cells in mice
- Can cancer chemotherapy enhance the malignant behaviour of tumours?
- In vivo emergence of a highly metastatic tumour cell line from a rat rhabdomyosarcoma after treatment with an alkylating agent.
- Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs
- Ribonucleotide reductase inhibitors: new strategies for cancer chemotherapy.
- Tyrosine and phenylalanine restriction induces G0/G1 cell cycle arrest in murine melanoma in vitro and in vivo.
- Interactions between cancer cells and the microvasculature: a rate-regulator for metastasis
- Can anticancer therapy be improved by sequential use of cytotoxic and cytostatic (differentiating or immunomodulating) agents to suppress tumor cell phenotypic diversification?
- Relationship between cell migration and cell cycle during the initiation of epithelial to fibroblastoid transition.
- Preneoplastic rat liver cells in vitro: Slow progression without promoters, hormones, or growth factors
- Effect of COX and LOX inhibitors on melanoma
- Cell‐cycle‐dependent invasion in vitro by rat ascites hepatoma cells
- Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex
- Selection of metastatic variants with identifiable karyotypic changes from a nonmetastatic murine tumor after treatment with 2'-deoxy-5-azacytidine or hydroxyurea: implications for the mechanisms of tumor progression.
- Prodding the Beast: Assessing the Impact of Treatment-Induced Metastasis.
- [Effect of anticancer drugs on invasive capacity of human small-cell lung cancer cells in vitro].
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