Possible involvement of reorganization of actin filaments, induced by tumor‐promoting phorbol esters, in changes in colony shape and enhancement of proliferation of cultured epithelial cells
Explore this paper's citation graph
Summary
The results suggest that TPA‐induced reorganization of actin filaments which can be inhibited by cyclic AMP results in changes in the shape of colonies and enhancement of proliferation.
- Type
- article
- Published
- 1987-07-01
- Cited by
- 24
- References
- 43
- OpenAlex
- https://openalex.org/W3036893
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23516258
Keywords
Computer science
References
- Tumor promoters induce changes in the chick embryo fibroblast cytoskeleton.
- Ultrastructural and biochemical changes induced in mouse epidermis by a hyperplastic agent, ethylphenylpropiolate.
- Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth.
- Interaction of tumour promoters with epithelial cells in culture. An immunofluorescence study.
- Differential response of premalignant epithelial cell classes to phorbol ester tumor promoters and to deoxycholic acid.
- Ornithine decarboxylase induction and DNA synthesis in hamster embryo cell cultures treated with tumor-promoting phorbol diesters.
- Ultrastructural, histological, and biochemical alterations produced by 12-O-tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin tumor promotion.
- Tumour promoter-mediated reversible inhibition of cell-cell communication (electrical coupling). Relationship with phorbol ester binding and de novo macromolecule synthesis.
- Effects of varying the dietary concentration of phenobarbital on its enhancement of 2-acetylaminofluorene-induced hepatic tumorigenesis.
- Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.
- Cell replacement in epidermis (keratopoiesis) via discrete units of proliferation.
- Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin.
- MODULATION OF TERMINAL DIFFERENTIATION AND RESPONSES TO TUMOR PROMOTERS BY RETINOIDS IN MOUSE EPIDERMAL CELL CULTURES
- On the Role of Microfilaments In Cell‐Shape‐Mediated Growth Control of Lens Epithelial Cells
- Tumor promoters cause a rapid and reversible inhibition of the formation and maintenance of electrical cell coupling in culture.
- Cellular transformation and the ‘morphologic phenotype’ of transformed cells
- Dihydrocytochalasin B disorganizes actin cytoarchitecture and inhibits initiation of DNA synthesis in 3T3 cells.
- The tumor promoter, 12-O-tetradecanoylphorbol-13-acetate accelerates keratinocyte differentiation and stimulates growth of an unidentified cell type in cultured human epidermis.
- Saccharin: from carcinogen to promoter
- Contact inhibition and malignancy
Cited by
- Intercellular Communication in Bronchial Epithelial Cells: Review of Evidence for a Possible Role in Lung Carcinogenesis
- Vasopressin‐induced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: Possible involvement of protein kinase C
- Effect of tight junctional resistance on penetration of LLC-PK1 epithelial cell layers by metastatic B16-F10 melanoma cells.
- Suppression by herbimycin A of 12-O-tetradecanoylphorbol-13-acetate-induced dissociation of cells and morphological changes in cultured FL and MDCK cells.
- Transition metal chelator TPEN counteracts phorbol ester–induced actin cytoskeletal disruption in C6 rat glioma cells without inhibiting activation or translocation of protein kinase C
- Modulation of survival and proliferation of BSC-1 cells through changes in spreading behavior caused by the tumor-promoting phorbol ester TPA.
- Intercellular contacts and the organization of actin filaments in cultured epithelial FL cells are altered by growth on type I collagen and treatment with 12-O-tetradecanoylphorbol-13-acetate through the modulation of interactions between cells and the substratum.
- The different effects of type I and IV collagens on the survival and proliferation of cultured BSC-1 cells.
- 12-O-tetradecanoylphorbol-13-acetate disrupts actin filaments and focal contacts and enhances binding of fibronectin-coated latex beads to 3T3-L1 cells.
- Tetrodotoxin suppresses morphological enhancement of the metastatic MAT-LyLu rat prostate cancer cell line
- Mammary Fibroblast‐derived Hepatocyte Growth Factor Stimulates Growth and Morphogenesis of Mouse Mammary Tumor Cells in Primary Culture
- Enhanced binding of fibronectin-coated latex beads to quiescent 3T3-L1 cells is correlated with escape from growth arrest.
- Herbimycin A Suppresses the Reduction of Gap‐junctional Intercellular Communication Induced by Tumor‐promoting Phorbol Ester in 3T3‐L1 Cells
- The effect of 12‐O‐tetradecanoylphorbol‐13‐acetate on Sertoli cell morphology and cytoskeletal organization: an in vitro study by means of cryo‐SEM and fluorescent techniques
- Inhibition of gap‐junctional intercellular communication and enhanced binding of fibronectin‐coated latex beads by stimulation of DNA synthesis in quiescent 3T3‐L1 cells
- Different effects of TPA on two skin-derived cell lines: murine (HEL-30) and human (NCTC) epidermal cells.
- Phorbol ester-induced reorganization of the cytoskeleton in human fibroblasts during ageing in vitro.
- Adhesiveness and proliferation of epithelial cells are differentially modulated by activation and inhibition of protein kinase C in a substratum‐dependent manner
- The in vitro effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate on Sertoli cell morphology.
- Contribution of functional voltage‐gated Na+ channel expression to cell behaviors involved in the metastatic cascade in rat prostate cancer: I. lateral motility
Related papers
No related papers recorded.