Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene.
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Summary
The primary structure of normal abl protein was determined by sequencing the coding region of its cDNA, which contains two alternative 5' exons spliced to a common set of 3' exon to yield the two major abl RNA transcripts.
- Type
- article
- Published
- 1986-10-24
- Cited by
- 452
- References
- 51
- OpenAlex
- https://openalex.org/W3021337
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36324337
Keywords
Political science
References
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Cited by
- Absence of alternative splicing in bcr-abl mRNA in chronic myeloid leukemia cell lines.
- Abl tyrosine kinase in signal transduction and cell-cycle regulation.
- Deletion of exon b3 of the BCR gene in CML: easy breakpoint mapping by a two-round PCR.
- Bcr‐abl protein detection in peripheral blood mononuclear cells for follow‐up of chronic myelogenous leukaemia patients
- Fusion Tyrosine Kinases Induce Drug Resistance by Stimulation of Homology-Dependent Recombination Repair, Prolongation of G2/M Phase, and Protection from Apoptosis
- BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy.
- Uses of polymerase chain reaction in leukemia: detection of minimal residual disease and identification of novel genetic mutations.
- Detection of residual disease in pediatric B-cell precursor acute lymphoblastic leukemia by comparative phenotype mapping: a study of five cases controlled by genetic methods.
- THE ROLE OF SRC FAMILY TYROSINE KINASES IN BCR-ABL SIGNAL TRANSDUCTION AND CHRONIC MYELOGENOUS LEUKEMIA
- Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunization with a BCR-ABL breakpoint peptide.
- Investigating allosteric regulation of ABL and BCR-ABL kinases: Implications for small molecule inhibitors
- Development of a liposomal formulation for peptide delivery to serve as vaccine against chronic myeloid leukemia
- Molecular analysis of chromosome breakpoints.
- Mutations in the regulatory domains of bcr/abl-positive leukemias detected by solid-phase automated DNA sequencing.
- Closely related BCR/ABL oncogenes are associated with the distinctive clinical biologies of Philadelphia chromosome positive chronic myelogenous and acute lymphocytic leukemia.
- Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia.
- Screening and determination of gene function using randomized ribozyme and siRNA libraries.
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