Do neuroleptics impair learning in schizophrenic patients?
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Summary
Support is provided for the hypothesis that neuroleptics might impair incentive but not s-s associative learning in schizophrenics and this observation might lead to more efficient use of behavior modification programs in the treatment of schizophrenia.
- Type
- article
- Published
- 1990-05-01
- Cited by
- 45
- References
- 36
- OpenAlex
- https://openalex.org/W2119795565
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24235980
Keywords
Psychology, Brief Psychiatric Rating Scale, Associative learning, Haloperidol, Incentive
References
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- The use of brief isolation to suppress delusional and hallucinatory speech
- The Brief Psychiatric Rating Scale
- Pimozide attenuates acquisition of lever-pressing for food in rats.
- Multiple receptors for dopamine
- Main effects of current and pimozide on prepared and learned self-stimulation behaviors are on performance not reward.
- Characteristics of 3H-cis-flupenthixol binding to calf brain membranes.
- Effects of apomorphine and haloperidol on exploratory behavior and latent learning in mice
- Neuroleptic-induced "anhedonia" in rats: pimozide blocks reward quality of food.
- Reducing delusional speech in chronic, paranoid schizophrenics.
- A controlled clinical psychiatric study of the drug chlorpromazine.
- Recent studies of simple reaction time.
- Memory in functional psychosis.
- A homologous radioimmunoassay for human prolactin.
Cited by
- Cognitive Functioning in Schizophrenia
- Distinguishing between haloperidol's and decamethonium's disruptive effects on operant behavior in rats: use of measurements that complement response rate.
- Memory function in schizophrenia
- Human reward system activation is modulated by a single dose of olanzapine in healthy subjects in an event-related, double-blind, placebo-controlled fMRI study
- Behavioural Psychotherapy and Schizophrenia: The Past, the Present, and the Future
- Lu 35-138 ((+)-(S)-3-1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsychotic potential.
- Drug safety and efficacy evaluation of sertindole for schizophrenia
- Regional Differences in the Action of Antipsychotic Drugs: Implications for Cognitive Effects in Schizophrenic Patients
- Reversal of PCP-induced learning and memory deficits in the Morris’ water maze by sertindole and other antipsychotics
- Impaired verbal memory is associated with impaired motor performance in schizophrenia: relationship to brain structure.
- Recent and remote memory dissociation: medication effects and hippocampal function in schizophrenia.
- Atypical antipsychotic and compliance in schizophrenia
- Emerging role of sertindole in the management of schizophrenia
- Memory functioning in chronic and non-chronic schizophrenics, affectively disturbed patients and normal controls.
- Differential effects of iloperidone, clozapine, and haloperidol on working memory of rats in the delayed non-matching-to-position paradigm
- Memory in schizophrenia and affective disorders.
- Effects of clozapine, haloperidol and iloperidone on neurotransmission and synaptic plasticity in prefrontal cortex and their accumulation in brain tissue: an in vitro study.
- Prediction of social skill acquisition in schizophrenic and major affective disorder patients from memory and symptomatology.
- Sertindole, in contrast to clozapine and olanzapine, does not disrupt water maze performance after acute or chronic treatment.
- Neuropsychological performance in chronic schizophrenia in response to neuroleptic dose reduction.
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