Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme

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Summary

Results indicate that retroviral vectors expressing HIV-1 RNA-specific ribozymes can be used to confer resistance toAIDS, and the highest level of resistance to AIDS was observed in MT4 cells transformed with a vector containing a fusion tk-TAR promoter.

Type
article
Published
1991-10-01
Cited by
148
References
18

Keywords

Political science

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