The modulation of growth by HMBA in PKC overproducing HT29 colon cancer cells.

Marcos Antonio de Orellano · Biochemical and Biophysical Research Communications - BBRC · 1991

Summary

Although HMBA markedly inhibited the growth of the control cells, no inhibition was seen with the HT29-PKC7 cells, which may be relevant to the use of HMBA in combination with other agents in the therapy of specific cancers.

Type: article
Published: 1991-12-16
Cited by: 8
References: 11
DOI: https://doi.org/10.1016/0006-291x(91)91262-b
PubMed: https://pubmed.ncbi.nlm.nih.gov/1755860/
OpenAlex: https://openalex.org/W1755860
Semantic Scholar: https://api.semanticscholar.org/CorpusID:31095228

Keywords

Humanities, Art

References

Differential expression of protein kinase C isozymes and erythroleukemia cell differentiation.E. Melloni, S. Pontremoli, P.L. Viotti — 1989
Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppressionPaul M. Choi, Kam-Meng Tchou-Wong, I B Weinstein — 1990
Antagonistic interactions of hexamethylene bisacetamide in combination with 1-beta-D-arabinofuranosylcytosine, adriamycin and harringtonine on the growth and differentiation of HL-60 cells in vitro.Xiangbin Kong, Michael Fanucchi, Ting‐Chao Chou — 1988
Induction of differentiation in mouse neuroblastoma cells by hexamethylene bisacetamide.Clive Palfrey, Yosef Kimhi, Uriel Z. Littauer — 1977
The molecular heterogeneity of protein kinase C and its implications for cellular regulationYasutomi Nishizuka — 1988
Transport by the (Na+, K+) ATPase: Modulation by differentiation inducers and inhibition of protein synthesis in the MDCK kidney epithelial cell lineBrian G. Kennedy, Julia E. Lever — 1985
Differentiation-defective mutants of mouse embryonal carcinoma cells: response to hexamethylenebisacetamide and retinoic acid.Peter A. McCue, Klaus I. Matthaei, Makoto M. Taketo — 1983
Induction of the expression of differentiation-related antigens on human colon carcinoma cells by stimulating protein kinase C.Paul L. Baron — 1990
Bryostatins: potent, new mitogens that mimic phorbol ester tumor promoters.Jeffrey B. Smith, Lucinda Smith, George R. Pettit — 1985
Induction of morphological and functional differentiation of human promyelocytic leukemia cells (HL‐60) by compounds which induce differentiation of murine leukemia cellsSteven Collins, Amos Bodner, R. C. Ting — 1980
Phase I and pharmacologic study of hexamethylene bisacetamide in patients with advanced cancer.Eric K. Rowinsky, D S Ettinger, L B Grochow — 1986

Cited by

Alteration of membrane fatty acid composition and inositol phosphate metabolism in HT-29 human colon cancer cells.Atif B. Awad, Carol S. Fink, Peter J. Horvath — 1993
Expression patterns of protein kinase C isoenzymes are characteristically modulated in chronic pancreatitis and pancreatic cancer.James D. Evans, Philip Cornford, Andrew Dodson — 2003
Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agents.Andreas J. Gescher — 1992
Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acidsJudit E. Pongrácz, Penny Clark, John P. Neoptolemos — 1995
Protein kinase C isoenzyme patterns characteristically modulated in early prostate cancer.Philip Cornford, Jim Evans, Andrew Dodson — 1999
Overexpression of protein kinase C-beta1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells.Geng Hui Zhu, Benjamin Chun Yu Wong, Eric D. Slosberg — 2000
EXPRESSIO NO FPROTEI NKINAS E Cb 1CONFER SRESISTANCE T OTNFa -AN DPACLITAXEL-INDUCE DAPOPTOSI SI NHT-29 COLO NCARCINOM ACELLSRobert aCASTINO — 2001

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