Multiple restriction fragment length polymorphisms at the GLUT2 locus: GLUT2 haplotypes for genetic analysis of Type 2 (non-insulin-dependent) diabetes mellitus
Explore this paper's citation graph
Summary
The frequencies of GLUT2 restriction fragment length polymorphisms and haplotypes in 50 Type 2 diabetic subjects and 50 non-diabetic control subjects show no significant differences suggesting that it is unlikely that there is a single major defect of this gene contributing to the inherited susceptibility to Type 2 diabetes in a Caucasian population.
- Type
- article
- Published
- 1991-11-01
- Cited by
- 14
- References
- 16
- Access
- Open access
- OpenAlex
- https://openalex.org/W1685129
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8435618
Keywords
Computer science
References
- Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster
- Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues.
- Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
- Family of Glucose-Transporter Genes: Implications for Glucose Homeostasis and Diabetes
- Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein.
- Polymorphisms of GLUT2 and GLUT4 Genes: Use in Evaluation of Genetic Susceptibility to NIDDM in Blacks
- Two EcoRI RFLPs at the GLUT2 locus.
- Molecular Defects in Diabetes Mellitus
- Cloning and functional expression of a human pancreatic islet glucose-transporter cDNA.
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
- Patterns of polymorphism and linkage disequilibrium for cystic fibrosis.
- Detection of specific sequences among DNA fragments separated by gel electrophoresis.
- An ammo-acid substitution involved in phenylketonuria is in linkage disequilibrium with DNA haplotype 2
- Molecular Cloning: A Laboratory Manual
- UK prospective study of therapies of maturity-onset diabetes
Cited by
- Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals
- Affected sib-pair analysis of the GLUT1 glucose transporter gene locus in non-insulin-dependent diabetes mellitus (NIDDM): evidence for no linkage
- Variability of the pancreatic islet beta cell/liver (GLUT 2) glucose transporter gene in NIDDM patients
- Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes.
- Biologic Variability in Plasma Glucose, Hemoglobin A1c, and Advanced Glycation End Products Associated with Diabetes Complications
- NOVEL GENES IN THE LIVER OF DIABETIC PSAMMOMYS OBESUS
- Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study.
- Analysis of polymorphism of the GLUT2 promoter in NIDDM patients and its functional consequence to the promoter activity.
- Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.
- Production Development
- Familial NIDDM
- The Genetics of Non Insulin Dependent Diabetes Mellitus ( NIDDM ) in Africa
- Pathophysiologie des Diabetes mellitus Typ2
- risk of developing type 2 diabetes (SUR1) genes on the ABCC8 (GLUT2) and SLC2A2activity modifies the effect of SNPs in the