The multifaceted oncoprotein Tax: subcellular localization, posttranslational modifications, and NF-κB activation.

Keywords

Business, Medicine, Biology

References

• HTLV-1 Yin and Yang: Rex and p30 Master Regulators of Viral mRNA TraffickingHicham H. Baydoun, Marcia Bellon, Christophe Nicot — 2008
• PCAF Interacts with Tax and Stimulates Tax Transactivation in a Histone Acetyltransferase-Independent MannerAmalia Julián — 1999
• Modulation of p53 activity by IκBα: Evidence suggesting a common phylogeny between NF-κB and p53 transcription factorsJuan Carlos Rodríguez Murillo — 2005
• New regulators of NF-κB in inflammationXavier Laborda — 2008
• Tax protein of HTLV-1 destabilizes the complexes of NF-kappa B and I kappa B-alpha and induces nuclear translocation of NF-kappa B for transcriptional activation.Tsutomu Suzuki, Hiroshi Hirai, Takeshi Murakami — 1995
• The SUMO system: an overview.Helle D. Ulrich — 2009
• Tax protein of HTLV-1 interacts with the Rel homology domain of NF-kappa B p65 and c-Rel proteins bound to the NF-kappa B binding site and activates transcription.Takeshi Suzuki, Hiroshi Hirai, Minoru Yoshida — 1994
• Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies.Akira Hangaishi, Seishi Ogawa, Nobutake Imamura — 1996
• Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulationNobuyoshi Arima, Jerry A. Molitor, Matthew Ryan Smith — 1991
• Chemical studies of histone acetylation. The distribution of epsilon-N-acetyllysine in calf thymus histones.G. Vidali, Edward L. Gershey, V. G. Allfrey — 1968
• Mutations of the p53 gene in adult T-cell leukemia.Akihiko Sakashita, Toshio Hattori, Miller Cw — 1992
• Constitutive phosphorylation and turnover of I kappa B alpha in human T-cell leukemia virus type I-infected and Tax-expressing T cellsJudith Lacoste, Louisa Petropoulos, N Pépin — 1995
• Identification of p40x-responsive regulatory sequences within the human T-cell leukemia virus type I long terminal repeatJohn Brady, K T Jeang, Janet F. Duvall — 1987
• Infection of human natural killer (NK) cells with replication-defective human T cell leukemia virus type I provirus. Increased proliferative capacity and prolonged survival of functionally competent NK cells.K M Lo, Éric Vivier, Nathalie Rochet — 1992
• A suboptimal 5' splice site downstream of HIV-1 splice site A1 is required for unspliced viral mRNA accumulation and efficient virus replicationJoshua Madsen, C. Martin Stoltzfus — 2006
• Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia.Kisato Nosaka, Michiyuki Maeda, Sadahiro Tamiya — 2000
• Proliferative response of Tax1-transduced primary human T cells to anti-CD3 antibody stimulation by an interleukin-2-independent pathwayTsuyoshi Akagi, Kunitada Shimotohno — 1993
• Cytogenetic studies of human T-cell leukemia virus type I carriers. A family study.Takahiro Itoyama, Naoki Sadamori, Seiji Tokunaga — 1990
• HTLV-I tax gene product activates transcription via pre-existing cellular factors and cAMP responsive element.Chou‐Zen Giam, Yinzhe Xu — 1989
• Transdominant human T-cell lymphotropic virus type I TAX1 mutant that fails to localize to the nucleusScott D. Gitlin, Paul F. Lindholm, Susan J. Marriott — 1991

Cited by

• Tax Posttranslational Modifications and Interaction with Calreticulin in MT-2 Cells and Human Peripheral Blood Mononuclear Cells of Human T Cell Lymphotropic Virus Type-I-Associated Myelopathy/Tropical Spastic Paraparesis PatientsFernando Medina, Sebastián Quintremil, Carolina Alberti — 2014
• Tumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiaChristophe Nicot — 2015
• Tax secretion from peripheral blood mononuclear cells and tax detection in plasma of patients with human T‐lymphotropic virus‐type 1‐associated myelopathy/tropical spastic paraparesis and asymptomatic carriersFernando Medina, Sebastián Quintremil, Carolina Alberti — 2016
• MicroRNA regulation of viral immunity, latency, and carcinogenesis of selected tumor viruses and HIVLing Wang, Guangyu Li, Zhi Q. Yao — 2015
• Regulation of HTLV-1 Tax Stability, Cellular Trafficking and NF-κB Activation by the Ubiquitin-Proteasome PathwayAlfonso Lavorgna, Edward W. Harhaj — 2014
• A Non-SUMOylated Tax Protein Is Still Functional for NF-κB Pathway ActivationSabrina Pène, Laetitia Waast, Amandine Bonnet — 2014
• Viral Proteins Originated De Novo by Overprinting Can Be Identified by Codon Usage: Application to the “Gene Nursery” of DeltaretrovirusesAngelo Pavesi, Gkikas Magiorkinis, David Karlin — 2013
• A Transgenic Drosophila melanogaster Model To Study Human T-Lymphotropic Virus Oncoprotein Tax-1-Driven Transformation In VivoMargret Shirinian, Zakaria Kambris, Lama Hamadeh — 2015
• Complex role of microRNAs in HTLV-1 infectionsGavin C. Sampey, Rachel Van Duyne, Robert Currer — 2012
• Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite GrowthSebastián Quintremil, Carolina Alberti, Matías Rivera — 2016
• Highlights on distinctive structural and functional properties of HTLV Tax proteinsMaria Grazia Romanelli, Erica Diani, Elisa Bergamo — 2013
• Inducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphomaHicham H. Baydoun, Mathew Cherian, Patrick Green — 2015
• HTLV Tax: A Fascinating Multifunctional Co-Regulator of Viral and Cellular PathwaysRobert Currer, Rachel Van Duyne, E Jaworski — 2012
• Animal models on HTLV-1 and related viruses: what did we learn?Hiba El Hajj, Rihab Nasr, Youmna Kfoury — 2012
• Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 proteinMarco Turci, Julie Lodewick, Gianfranco Di Gennaro — 2012
• Xenotransplantation elicits salient tumorigenicity of adult T‐cell leukemia‐derived cells via aberrant AKT activationKazunori Yamaguchi, Tomoka Takanashi, Kentaro Nasu — 2016
• The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 OncoproteinGreta Forlani, Rawan Abdallah, Roberto S. Accolla — 2016
• Human proteins with target sites of multiple post-translational modification types are more prone to be involved in disease.Qianli Huang, Jinhui Chang, Man Kit Cheung — 2014
• [Unanchored ubiquitin chains: a new viral target for NF-κB activation].Aurélien Schwob, Renaud Mahieux, Chloé Journo — 2016
• ATL-derived exosomes modulate mesenchymal stem cells: potential role in leukemia progressionJamal El Saghir, Farah Nassar, Nadim Tawil — 2016

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