Materials and Methods Briefdefinitive Report Disseminated Tuberculosis in Interferon 7 Gene-disrupted Mice
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Summary
It is shown that mice in which the IFN-y gene has been disrupted were unable to contain or control a normally sublethal dose of M. tuberculosis, and results indicate that IFN-'Y plays a pivotal role in the expression of protective immunity to this infection in the mouse.
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