An integrative omics-guided druggability analysis of VCX2 in hepatocellular carcinoma using Peruvian natural products
Explore this paper's citation graph
Summary
These findings support VCX2 as a potential molecular target in HCC and highlight luteolin-5-O-glucoside as a promising lead scaffold.
- Type
- article
- Published
- 2026-05-18
- Cited by
- 0
- References
- 138
- Access
- Open access
- OpenAlex
- https://openalex.org/W7161558371
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:288501069
Keywords
Druggability, Virtual screening, Hepatocellular carcinoma, Transcriptome, Gene
References
- Ribosomal proteins and colorectal cancer.
- Analysis of the VCX3A, VCX2 and VCX3B genes shows that VCX3A gene deletion is not sufficient to result in mental retardation in X‐linked ichthyosis
- Small-molecule library screening by docking with PyRx.
- RPL41, a small ribosomal peptide deregulated in tumors, is essential for mitosis and centrosome integrity.
- Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor’s proangiogenic microenvironment
- Glycosaminoglycans and their proteoglycans: host‐associated molecular patterns for initiation and modulation of inflammation
- SMILES, a chemical language and information system. 1. Introduction to methodology and encoding rules
- Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors.
- EMT, the cytoskeleton, and cancer cell invasion
- TMBIM protein family: ancestral regulators of cell death
- Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers
- X inactive-specific transcript RNA coating and genetic instability of the X chromosome in BRCA1 breast tumors.
- The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide.
- Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity.
- Regulation of PDGF and its receptors in fibrotic diseases.
- The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages
- Steroid sulfatase: molecular biology, regulation, and inhibition.
- APOA2 Polymorphism in Relation to Obesity and Lipid Metabolism
- PI3K/Akt and apoptosis: size matters
- Gender Differences of B Cell Signature in Healthy Subjects Underlie Disparities in Incidence and Course of SLE Related to Estrogen
Cited by
No citing papers recorded for this paper.
Related papers
No related papers recorded.