Mechanisms biomarkers and therapeutic strategies of human endogenous retroviruses in cancer
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Summary
A convergent translational framework—leveraging international consortia for biomarker validation, machine learning for patient stratification, and engineered tumor-selective delivery platforms—is now positioned to harness this novel target class and redefine the next era of precision oncology.
- Type
- article
- Published
- 2026-04-16
- Cited by
- 0
- References
- 62
- Access
- Open access
- OpenAlex
- https://openalex.org/W7154577109
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:287567539
Keywords
Cancer, Carcinogenesis, Immunosurveillance, Endogenous retrovirus, Epigenetics
References
- Expression profiles of human endogenous retrovirus (HERV)-K and HERV-R Env proteins in various cancers
- Allele-specific epigenetic activity in prostate cancer and normal prostate tissue implicates prostate cancer risk mechanisms
- Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/− Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets
- Advancements in Human Breast Cancer Targeted Therapy and Immunotherapy
- Mechanism of Human Endogenous Retrovirus (HERV) in Inflammatory Response
- A Systematic Review of Expression and Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches
- NF-κB-Induced R-Loops and Genomic Instability in HTLV-1-Infected and Adult T-Cell Leukemia Cells
- Integration of TE Induces Cancer Specific Alternative Splicing Events
- PubChem 2023 update
- Single-cell RNA sequencing highlights the functional role of human endogenous retroviruses in gallbladder cancer
- Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
- The Immunological Conundrum of Endogenous Retroelements
- HERVs and Cancer—A Comprehensive Review of the Relationship of Human Endogenous Retroviruses and Human Cancers
- Prostate cancer autoantibodies - applications in diagnosis, prognosis, monitoring disease progression and immunotherapy.
- Advances in next-generation sequencing and emerging technologies for hematologic malignancies
- Single‑cell multi‑omics advances in lymphoma research (Review).
- Effect of different metastasis patterns on the prognosis of patients with stage III high-grade serous ovarian cancer.
- Comparison of quantitative PCR and digital PCR assays for quantitative detection of infectious bronchitis virus (IBV) genome.
- Epigenetic modulation of antitumor immunity and immunotherapy response in breast cancer: biological mechanisms and clinical implications
- Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
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