ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction

Keywords

Medicine, Captopril, Placebo, Myocardial infarction, Cardiogenic shock

References

• Randomized controlled trial of oral captopril, of oral isosorbide mononitrate and of intravenous magnesium sulphate started early in acute myocardial infarction: safety and haemodynamic effects. ISIS-4 (Fourth International Study of Infarct Survival) Pilot Study Investigators.Marcus Flather, Athanase Pipilis, Rory Collins — 1994
• Intravenous magnesium for acute myocardial infarction.Jing Li, Qing Zhang, Mingming Zhang — 2007
• Application of Bayesian statistics to decision making during a clinical trial.Laurence S. Freedman, David J. Spiegelhalter — 1992
• Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)KL Woods, Nick Fletcher — 1994
• Endothelium‐dependent relaxation in coronary arteries requires magnesium ionsBella T. Altura, Burton M. Altura — 1987
• Does captopril treatment before thrombolysis in acute myocardial infarction attenuate reperfusion damage? Short-term and long-term effects.Pietro Di Pasquale, Salvatore Paterna, Sergio Cannizzaro — 1994
• Expansion of Transmural Myocardial Infarction A Pathophysiologic Factor in Cardiac RuptureEdward H. Schuster, Bernadine H. Bulkley — 1979
• A randomized placebo-controlled trial of combined early intravenous captopril and recombinant tissue-type plasminogen activator therapy in acute myocardial infarction.Elizabeth G. Nabel, Eric J. Topol, Anita Galeana — 1991
• Neuroendocrine activation after acute myocardial infarction.Howard M. McAlpine, J. J. Morton, B Leckie — 1988
• Effects of lisinopril and nitroglycerin on blood pressure early after myocardial infarction: The GISSI‐3 pilot studyRoberto Latini, Fausto Avanzini, Andrea De Nicolao — 1994
• The ESPRIM trial: short-term treatment of acute myocardial infarction with molsidomine*1EUROPEANSTUDYOFPREVENTIONOFIN — 1994
• Ventricular Remodeling After Myocardial Infarction: Experimental Observations and Clinical ImplicationsMarc A. Pfeffer, Eugene Braunwald — 1990
• Persistent improvement in left ventricular geometry and function by prolonged nitroglycerin therapy after anterior transmural acute myocardial infarctionBodh I. Jugdutt, James Neiman, Bogdan L. Nichorowski — 1990
• ACE inhibition in acute myocardial infarction.Marc A. Pfeffer — 1995
• Effect of intravenous nitrates on mortality in acute myocardial infarction: an overview of the randomised trials.Salim Yusuf, Stephen MacMahon, Rory Collins — 1988
• Early prevention of left ventricular dysfunction after myocardial infarction with angiotensin-converting-enzyme inhibition.Norman Sharpe, Hans‐Jørgen Smith, Judy Murphy — 1991
• Comparison of enalapril versus captopril on left ventricular function and survival three months after acute myocardial infarction (the "PRACTICAL" study).S. G. Foy, Ian Crozier, John G. Turner — 1994
• LONG‐TERM THERAPEUTIC EFFICACY WITH ONCE‐DAILY ISOSORBIDE‐5‐MONONITRATE (IMDUR®)M. J. Kendall — 1990
• Cardiac myocyte necrosis induced by angiotensin II.Lip Bun Tan, Jorge Jalil, R Pick — 1991
• Clinical trial monitoring: hit or miss?Jon Cohen — 1994

Cited by

• Pharmacological Prevention of Reperfusion Injury in Acute Myocardial InfarctionMiguel Quintana, Thomas Kahan, Paul Hjemdahl — 2004
• Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis.Jonathan A C Sterne, Matthias Egger — 2001
• Prävention des linksventrikulären RemodelingsThomas Thum, Georg Ertl, Johann Bauersachs — 2008
• Mortality as an Outcome in Sepsis TrialsPaul C. Hébert — 1997
• Risk stratification following myocardial infarction in the thrombolytic era: a two-step strategy using noninvasive and invasive methods.Dietrich Andresen, Gerhard Steinbeck, Thomas Brüggemann — 1999
• Effects of captopril on ventricular arrhythmias in the early and late phase of suspected acute myocardial infarction. Randomized, placebo-controlled substudy of ISIS-4.Andrzej Budaj, Jacek Cybulski, Krzysztof Cedro — 1996
• [Marihuana and cannobinoids as medicaments].Marek Tkaczyk, Ewa Florek, Wojciech Piekoszewski — 2012
• New Agents, New Trials, New SolutionsRobert M. Califf, Robert A. Harrington — 1998
• Analisi costo-efficacia dell’impiego precoce di lisinopril nei pazienti con infarto miocardico acutoMaria Grazia Franzosi, Aldo P. Maggioni, Eugenio Santoro — 2000
• Update on the Use of Magnesium as an Antiarrhythmic DrugTerence John Campbell — 2000
• Aspirin and ACE-inhibitors: for Wedding or Funeral?Israel M. Barbash, Shmuel Gottlieb, Uri Goldbourt — 2001
• Does nitroglycerin therapy hit the endothelium?Thomas Münzel — 2001
• Captopril Does Not Influence the Components of Free Radical Activity Following Acute Myocardial InfarctionK Herbaczyńska-Cedro, Beata Kłosiewicz-Wąsek — 2000
• Systematic Reviews: What can They do for You?Lelia Duley — 1996
• Antiarrhythmic Impact of Anti-Ischemic, Anti-Failure and Other Cardiovascular StrategiesMichael J. Reiter — 2000
• Recently Developed Neuroprotective Therapies for Acute StrokePaul Dorman, Carl Counsell, Peter Sandercock — 1996
• Nitrate-induced toxicity and preconditioning: a rationale for reconsidering the use of these drugs.Tommaso Gori, John D. Parker — 2008
• Therapy for acute myocardial infarction.Michael W. Rich — 1996
• Medikamentöse Therapie zur Prognoseverbesserung nach akutem MyokardinfarktRoland Willenbrock, Jan Monti, Rainer Dietz — 1999
• Late Coronary Artery Reperfusion has Additive Beneficial Effects on Infarct Expansion when Combined with Early Angiotensin Converting Enzyme Inhibitor Therapy Post Myocardial InfarctionThierry Duchatellier, Edward J. Brown, Imad A. Alhaddad — 2004

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