The Familial Parkinsonism Gene LRRK2 Regulates Neurite Process Morphology
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- Type
- article
- Published
- 2006-11-01
- Cited by
- 568
- References
- 19
- Access
- Open access
- OpenAlex
- https://openalex.org/W2122072833
Keywords
LRRK2, Neurite, Leucine-rich repeat, Parkinsonism, Biology
References
- Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism
- Neurite outgrowth in peripherin-depleted PC12 cells
- A Role for Synaptotagmin VII-Regulated Exocytosis of Lysosomes in Neurite Outgrowth from Primary Sympathetic Neurons
- The Protein Kinase Complement of the Human Genome
- Parkinsonism genes: culprits and clues
- Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity.
- Autosomal dominant parkinsonism associated with variable synuclein and tau pathology
- Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
- How MAP Kinases Are Regulated (*)
- LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages
- Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
- Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity.
- A Common Exocytotic Mechanism Mediates Axonal and Dendritic Outgrowth
- Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.
- The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.
- Mutations of the BRAF gene in human cancer
Cited by
- LRRK2: an éminence grise of Wnt-mediated neurogenesis?
- [Progression of gestational hypertension to preeclampsia].
- The Impact of Genetic Research on Our Understanding of Parkinson’s Disease
- THE ROLE OF DOPAMINE OXIDATION IN DOPAMINE-INDUCED TOXICITY, INITIATION OF ENDOPLASMIC RETICULUM STRESS, AND POTENTIATION OF ROTENONE-INDUCED TOXICITY IN DIFFERENTIATED PC12 CELLS
- Investigating the Multiple Hit hypothesis of Parkinson disease using transgenic LRRK2-R1441G rats
- A new rodent model of Parkinson s Disease based on neuron specific downregulation of glutathione production.
- The role of kalirin-7 in the pathogenesis of Parkinson disease and Huntington disease
- LRRK2 genetics and expression in the Parkinsonian brain
- LRRK2 Regulates Actin Dynamics in ADP-Treated Microglia
- LRRK2 Pathways Leading to Neurodegeneration
- Signal Transduction Pathways Modulated by the PD-causative Gene LRRK2
- Functional characterization of leucine-rich repeat kinase 2 (LRRK2) dimerization
- Establishment and characterization of a human in vitro cell model for Parkinson 's Disease
- An Early Axonopathy in a hLRRK2(R1441G) Transgenic Model of Parkinson Disease
- Connecting Ca2+ Stores and Parkinson Disease
- Unraveling the role of defective genes
- Genetic mouse models of neurodegenerative diseases.
- From the baker to the bedside: yeast models of Parkinson's disease
- Getting connected in the dopamine system.
- Intracellular signalling pathways in dopamine cell death and axonal degeneration
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- Glucocerebrosidase mutations are not found in association with LRRK2 G2019S in subjects with parkinsonism.
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- Chemical Biology of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors.
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