Redox Balance in Cancer in the Context of Tumor Prevention and Treatment
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Summary
The review offers a comprehensive overview of the existing knowledge on oxidation and reduction processes in cancer, concluding that personalized and precise anticancer therapies targeting the redox processes can serve as both effective diagnostic and therapeutic tools.
- Type
- review
- Published
- 2025-05-01
- Cited by
- 15
- References
- 192
- Access
- Open access
- OpenAlex
- https://openalex.org/W4410239948
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:278470587
Keywords
Context (archaeology), Medicine, Cancer, Cancer prevention, Intensive care medicine
References
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- NAD(P)H, a directly operating antioxidant?
- Oxidative stress: a concept in redox biology and medicine
- The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells.
- Relation between Gastric Cancer and Protein Oxidation, DNA Damage, and Lipid Peroxidation
- Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.
- Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy
- Beta‐carotene in multivitamins and the possible risk of lung cancer among smokers versus former smokers
- Superoxide dismutase in gastric adenocarcinoma: is it a clinical biomarker in the development of cancer?
- Glucose-6-Phosphate Dehydrogenase, NADPH, and Cell Survival
- Suppression of prostate cancer in a transgenic rat model via γ‐tocopherol activation of caspase signaling
- Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study.
- Antioxidant vitamin and mineral supplementation and prostate cancer prevention in the SU.VI.MAX trial
- Unconjugated bilirubin induces apoptosis in colon cancer cells by triggering mitochondrial depolarization
Cited by
- Oxidative Stress-Driven Cellular Senescence: Mechanistic Crosstalk and Therapeutic Horizons
- Revolutionizing Breast Cancer Treatment: Harnessing Ehrlich Ascites Carcinoma Model, Cancer Metabolism, and Nanotechnology-Enhanced Chemotherapy for Improved Patient Outcomes.
- Redox Homeostasis as a Therapeutic Target in Chronic Oxidative Diseases: Implications for Cancer Treatment
- Beyond Metal Removal: Microbial Strategies for Copper and Zinc Detoxification and Implications for Aquatic Fish Health
- Redox enzyme networks shaping cancer drug metabolism and therapeutic resistance
- Concurrent Ferroptosis and Apoptosis in Resveratrol‐Treated Glioblastoma Cells: Relevance With NRF2 Downregulation and Oxidative Stress
- Design, computational profiling, synthesis and biological evaluation of novel 1,2,4-triazole based derivatives as antioxidant and potent p53-MDM2 inhibitors.
- Comprehensive pan-cancer analysis of AARS1, a newly identified lactyltransferase in human cancers
- OXIDATIVE STRESS–DRIVEN THYROID CARCINOGENESIS: MECHANISTIC PERSPECTIVES AND TARGETED INTERVENTIONS
- Systemic dysregulation of essential and toxic elements and redox homeostasis in gynecologic malignancies
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