Differences in cerebral spontaneous neural activity correlate with gene-specific transcriptional signatures in primary angle-closure glaucoma.
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Summary
This study establishes a connection between the molecular mechanisms of PACG and alterations in brain function and gene expression, providing valuable perspectives on the fundamental processes impacting low-frequency oscillations in PACG.
- Type
- article
- Published
- 2024-12-01
- Cited by
- 8
- References
- 53
- OpenAlex
- https://openalex.org/W4405133417
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:274568249
Keywords
Transcriptome, Biology, Gene, Genetics, Resting state fMRI
References
- Altered functional connectivity density in primary angle-closure glaucoma patients at resting-state.
- Disrupted interhemispheric functional connectivity in primary angle-closure glaucoma: a functional MRI study: voxel-mirrored homotopic connectivity in primary angle-closure glaucoma patients
- Multivariate classification of autism spectrum disorder using frequency-specific resting-state functional connectivity--A multi-center study.
- Disturbed spontaneous brain activity pattern in patients with primary angle-closure glaucoma using amplitude of low-frequency fluctuation: a fMRI study
- Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data.
- Primary angle‐closure glaucoma: an update
- Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma.
- May glutathione S-transferase M1 positive genotype afford protection against primary open-angle glaucoma?
- Cerebellar neurocognition: insights into the bottom of the brain.
- Metabolic abnormalities in patients with primary open-angle glaucoma.
- Expression of the primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 in endothelial and epithelial cell junctions in the eye.
- Frequency‐specific alternations in the amplitude of low‐frequency fluctuations in schizophrenia
- Family history is a strong risk factor for prevalent angle closure in a South Indian population.
- DPARSF: A MATLAB Toolbox for “Pipeline” Data Analysis of Resting-State fMRI
- Amplitude of low-frequency oscillations in schizophrenia: A resting state fMRI study
- The Oscillating Brain: Complex and Reliable
- T-Helper1/T-Helper2 Cytokine Imbalance in the Iris of Patients with Glaucoma
- Circadian rhythm dysfunction in glaucoma: A hypothesis
- Scaling of Neural Responses to Visual and Auditory Motion in the Human Cerebellum
- Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts
Cited by
- Potential impact of Helicobacter pylori infection on primary-angle closure glaucoma and primary open-angle glaucoma pathophysiology.
- Multimodal neuroimaging alterations and host genetic associations in patients with rhegmatogenous retinal detachment: a transcriptomic-neuroimaging study
- Abnormal functional lateralization and functional connectivity in thyroid-associated ophthalmopathy: mechanistic links to transcriptomic signatures and neurotransmitter systems.
- Differences in the amplitude of dynamic low-frequency fluctuations in primary angle-closure glaucoma are associated with gene-molecular multi-omics
- Cortical gradient compression links cognition and transcriptomic signatures in primary angle-closure glaucoma
- Static and dynamic perspective on brain activity and functional connectivity alternations in the comorbidity of chronic pain and depression: An fMRI study in rats
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