Drug and Protein Interaction Network Construction for Drug Repurposing in Alzheimer’s Disease
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Summary
The approach offers a promising method for treating various diseases by repurposing existing drugs, thereby reducing the cost and time of experimental procedures and paving the way for more precise Network Medicine strategies.
- Type
- article
- Published
- 2023-10-12
- Cited by
- 4
- References
- 45
- Access
- Open access
- OpenAlex
- https://openalex.org/W4387572939
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:264064519
Keywords
DrugBank, Drug repositioning, Repurposing, Interaction network, Drug discovery
References
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- The Moving Frontier in Nitric Oxide–Dependent Signaling
- Association between APOC1 Polymorphism and Alzheimer’s Disease: A Case-Control Study and Meta-Analysis
- Protein S-nitrosylation in health and disease: a current perspective
- Neuroprotective properties of Bcl‐w in Alzheimer disease
- Overexpression of GRK2 in alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions
- The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl‐leukotrienes receptor
- Regulation of Cell Survival Mechanisms in Alzheimer's Disease by Glycogen Synthase Kinase-3
- Astrocytes in Alzheimer’s disease
- Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains
- Serum Levels of ApoA1 and ApoA2 Are Associated with Cognitive Status in Older Men
- Integrative methods for analyzing big data in precision medicine
- Function of Metallothionein-3 in Neuronal Cells: Do Metal Ions Alter Expression Levels of MT3?
- ATP1A3-related disorders: An update.
- SCANPY: large-scale single-cell gene expression data analysis
- Network-based approach to prediction and population-based validation of in silico drug repurposing
- The drug repurposing landscape from 2012 to 2017: evolution, challenges, and possible solutions.
- Platinum(II) O,S Complexes Inhibit the Aggregation of Amyloid Model Systems
- Efficient integration of heterogeneous single-cell transcriptomes using Scanorama
- Molecular characterization of selectively vulnerable neurons in Alzheimer’s Disease
Cited by
- Prediction of Protein–Protein Interactions Based on Integrating Deep Learning and Feature Fusion
- Network pharmacology approach to unravel the neuroprotective potential of natural products: a narrative review
- Prioritizing repurposable drugs for Alzheimer’s disease using network-based analysis with concurrent assessment of Long QT syndrome risk
- SCMPPI: Supervised Contrastive Multimodal Framework for Predicting Protein-Protein Interactions
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