Circulating mutant DNA to assess tumor dynamics
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Summary
It is found that ctDNA measurements could be used to reliably monitor tumor dynamics in subjects with cancer who were undergoing surgery or chemotherapy, and it is suggested that this personalized genetic approach could be generally applied to individuals with other types of cancer.
- Type
- article
- Published
- 2008-07-31
- Cited by
- 2,350
- References
- 15
- Access
- Open access
- OpenAlex
- https://openalex.org/W4235642752
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5291558
Keywords
Circulating tumor DNA, Colorectal cancer, Somatic cell, Cancer, DNA
References
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- Carcinoembryonic Antigen in the Staging and Follow-up of Patients with Colorectal Cancer
- Tumor microenvironment: The role of the tumor stroma in cancer
- Circulating free DNA in plasma or serum as biomarker of carcinogenesis: practical aspects and biological significance.
- Circulating tumor cells, disease progression, and survival in metastatic breast cancer.
- Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations
- Circulating Nucleic Acids in Plasma or Serum (CNAPS) as Prognostic and Predictive Markers in Patients with Solid Neoplasias
- Mutational analysis using oligonucleotide microarrays
- The Genomic Landscapes of Human Breast and Colorectal Cancers
Cited by
- Uterine cervix carcinoma: recent biological data and update for improving follow-up and treatment.
- Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non–Small Cell Lung Cancer Patients
- A PIK3CA mutation detected in plasma from a patient with synchronous primary breast and lung cancers
- Outcomes and endpoints in trials of cancer treatment: the past, present, and future.
- ESR1 mutations in circulating plasma tumor DNA from metastatic breast cancer patients
- Detection of circulating tumor DNA in patients with advanced non-small cell lung cancer
- Liquid Biopsy: A Future Tool for Posttreatment Surveillance in Head and Neck Cancer?
- Post surgery circulating free tumor DNA is a predictive biomarker for relapse of lung cancer
- Clinical utility of circulating DNA analysis for rapid detection of actionable mutations to select metastatic colorectal patients for anti-EGFR treatment
- Emerging uses of circulating tumor DNA in advanced stage non-small cell lung cancer.
- Centrifugation-free extraction of circulating nucleic acids using immiscible liquid under vacuum pressure
- The Clinical Landscape of Circulating Tumor DNA in Gastrointestinal Malignancies
- Utility of targeted deep sequencing for detecting circulating tumor DNA in pancreatic cancer patients
- Liquid Biopsy in Prostate Cancer: Circulating Tumor Cells and Beyond
- Pt-induced crosslinks promote target enrichment and protection from serum nucleases
- TNER: a novel background error suppression method for mutation detection in circulating tumor DNA
- ASO Author Reflections: Circulating Tumor DNA in Peritoneal Carcinomatosis
- Clinical Validation of a Cell-Free DNA Gene Panel.
- Application of liquid biopsy for surgical management of pancreatic cancer
- Opportunities on the horizon for the management of early colon cancer.
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