Stearylated Macropinocytosis-Inducing Peptides Facilitating the Cellular Uptake of Small Extracellular Vesicles.
Explore this paper's citation graph
Summary
This study aims to endow P4A and related peptides with the ability to induce macropinocytosis in the presence of serum by N-terminal acylation with long-chain fatty acids (i.e., decanoic, myristic, and stearic acids).
- Type
- article
- Published
- 2022-05-04
- Cited by
- 11
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W4229036759
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:248514638
Keywords
Pinocytosis, Chemistry, Endocytosis, Intracellular, Extracellular
References
- Cationic PTD/CPP-mediated macromolecular delivery: charging into the cell
- Adenovirus-induced leakage of co-endocytosed macromolecules into the cytosol.
- Lifeact: a versatile marker to visualize F-actin
- Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate
- The Role of Basal Insulin and Glucagon-Like Peptide-1 Agonists in the Therapeutic Management of Type 2 Diabetes—A Comprehensive Review
- Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake
- Interaction of arginine-rich peptides with membrane-associated proteoglycans is crucial for induction of actin organization and macropinocytosis.
- Virus entry by macropinocytosis
- Trafficking and function of the tetraspanin CD63.
- Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement.
- A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages
- Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides
- A comprehensive overview of exosomes as drug delivery vehicles - endogenous nanocarriers for targeted cancer therapy.
- Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans.
- Regulated portals of entry into the cell
- Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling
- Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes
- Extracellular vesicles for drug delivery.
- Syndecan-4 Is a Receptor for Clathrin-Mediated Endocytosis of Arginine-Rich Cell-Penetrating Peptides.
- Effect of self-association of bovine serum albumin on the stability of surfactant-induced aggregates of allylamine-capped silicon quantum dots.
Cited by
- Extracellular Vesicles in Myeloid Neoplasms
- Molecular Docking and Intracellular Translocation of Extracellular Vesicles for Efficient Drug Delivery
- Role of Ceramides and Lysosomes in Extracellular Vesicle Biogenesis, Cargo Sorting and Release
- Targeted drug delivery system inspired by macropinocytosis.
- Cell-Surface-Retained Peptide Additives for the Cytosolic Delivery of Functional Proteins
- Methods, Mechanisms, and Application Prospects for Enhancing Extracellular Vesicle Uptake.
- Finding ways into the cytosol: Peptide-mediated approaches for delivering proteins into cells.
- SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein.
- Curvature-sensing peptide functions as a membrane interfactant that glues small extracellular vesicles to cell membranes and enhances vesicle cellular uptake
- Sars-Cov-2 Inhibition Through Mrna Delivery Using Engineered Extracellular Vesicles Displaying the Spike Protein
Related papers
- Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes.
- Study progress of cell endocytosis
- Endocytosis of peptide hormones and other ligands.
- Revealing macropinocytosis using nanoparticles
- Macropinocytosis.
- Cultivation of Dictyostelium discoideum in axenic medium.
- Study progress of cell endocytosis
- Endocytosis of Bacteriophages.
- Stimulated endocytosis in penetratin uptake: effect of arginine and lysine.
- M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages.