Ghrelin treatment induces rapid and delayed increments of food intake: a heuristic model to explain ghrelin’s orexigenic effects
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Summary
It is found that ghrelin primarily induces a biphasic effect on food intake that has indirect consequences on energy expenditure and nutrient partitioning and a heuristic model is proposed to describe how the orexigenic effect of gh Relin and the anorectic food intake-induced rebound sculpt a timely constrain feeding response to ghrelIn.
- Type
- article
- Published
- 2021-06-02
- Cited by
- 18
- References
- 81
- Access
- Open access
- OpenAlex
- https://openalex.org/W3170518085
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:236219630
Keywords
Ghrelin, Orexigenic, Endocrinology, Internal medicine, Food intake
References
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- Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice.
- Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein.
Cited by
- “Sibling” battle or harmony: crosstalk between nesfatin-1 and ghrelin
- GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner
- Role of the Ghrelin System in Colorectal Cancer
- Systemic Ghrelin Treatment Induces Rapid, Transient, and Asymmetric Changes in the Metabolic Activity of the Mouse Brain
- Ghrelin proteolysis increases in plasma of men, but not women, with obesity.
- Chlorpromazine, an Inverse Agonist of D1R-Like, Differentially Targets Voltage-Gated Calcium Channel (CaV) Subtypes in mPFC Neurons
- GHRELIN’S OREXIGENIC ACTION IN THE LATERAL HYPOTHALAMIC AREA INVOLVES INDIRECT RECRUITMENT OF OREXIN NEURONS AND ARCUATE NUCLEUS ACTIVATION
- Ghrelin-responsive mediobasal hypothalamic neurons mediate exercise-associated food intake and exercise endurance
- A NEW GRELIN RECEPTOR ANTAGONIST AGRELAX REDUCES EMOTIONAL OVEREATING CAUSED BY STIMULATION OF THE LATERAL HYPOTHALAMUS REWARD ZONE IN WELL-FED RATS
- Blunted anticipation, but not consummation, of food rewards in depression
- Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet
- Hypothalamic tanycytes internalize ghrelin from the cerebrospinal fluid: Molecular mechanisms and functional implications
- Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction.
- Liraglutide Induces Enhanced Suppression of Food Intake in Mice Lacking the Growth Hormone Secretagogue Receptor.
- Food restriction and amphetamine exposure synergistically enhance accumbal dopamine D1 receptor-mediated locomotor activity.
- GHSR agonism increases blood glucose but delays food intake in GHSR hyperresponsive rats
- AgRP neuron activity enhances reward-related consummatory behaviors during energy deficit in mice
- Blunted anticipation but not consummation of food rewards in depression
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