The CD8+ T Cell Noncytotoxic Antiviral Responses
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Summary
Since CNAR/CAF is a natural noncytotoxic activity, it could provide promising strategies for HIV/AIDS therapy, cure, and prevention.
- Type
- review
- Published
- 2021-05-12
- Cited by
- 26
- References
- 356
- Access
- Open access
- OpenAlex
- https://openalex.org/W3161369683
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:234484321
Keywords
Cytotoxic T cell, Biology, CTL*, CD8, Virology
References
- CD8+ cells from asymptomatic human immunodeficiency virus-infected individuals suppress superinfection of their peripheral blood mononuclear cells.
- Suppression of HIV replication in vitro by CD8+ T-cells from HIV-infected and HIV-seronegative individuals
- β-Chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans
- Suppression of HIV replication in the resting CD4+ T cell reservoir by autologous CD8+ T cells: implications for the development of therapeutic strategies.
- The CD8+ cell noncytotoxic anti-HIV response can be blocked by protease inhibitors
- Clinical features and determinants of chronicity in hepatitis E virus infection
- Sensitivity of human immunodeficiency virus infection to various alpha, beta and gamma chemokines.
- Patterns of T lymphocyte changes with human immunodeficiency virus infection: from seroconversion to the development of AIDS.
- Chemokines and HIV–1 second receptors
- CD8+ T cell mediated noncytolytic inhibition of human immunodeficiency virus type I.
- The balance between persistent virus infection and immune cells determines demyelination.
- CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells.
- HIV-infected humans, but not chimpanzees, have circulating cytotoxic T lymphocytes that lyse uninfected CD4+ cells.
- Detection of a vigorous HIV-1-specific cytotoxic T lymphocyte response in cerebrospinal fluid from infected persons with AIDS dementia complex.
- gamma-Interferon plays a key role in T-cell-induced tumor regression.
- IL-16 represses HIV-1 promoter activity.
- Cell-mediated suppression of HIV-specific cytotoxic T lymphocytes.
- Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.
- TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability
- Differential effects of CD28 costimulation on HIV production by CD4+ cells.
Cited by
- Vaccination against the Koala Retrovirus (KoRV): Problems and Strategies
- Monophosphoryl Lipid A Tolerance Against Chronic Stress-Induced Depression-Like Behaviors in Mice
- HIV Infection Predisposes to Increased Chances of HBV Infection: Current Understanding of the Mechanisms Favoring HBV Infection at Each Clinical Stage of HIV Infection
- Highly dampened HIV-specific cytolytic effector T cell responses define viremic non-progression
- CCL5-Secreting Virtual Memory CD8+ T Cells Inversely Associate With Viral Reservoir Size in HIV‐1−Infected Individuals on Antiretroviral Therapy
- Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV
- CD38: An important regulator of T cell function.
- Non-cytotoxic functions of CD8 T cells: “repentance of a serial killer”
- Preclinical immunogenicity assessment of a cell-based inactivated whole-virion H5N1 influenza vaccine
- Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay
- HIV reservoir: antiviral immune responses and immune interventions for curing HIV infection
- CD8+ Lymphocytes from Healthy Blood Donors Secrete Antiviral Levels of Interferon-Alpha
- Stochastic virus infection model with Ornstein–Uhlenbeck perturbation: Extinction and stationary distribution analysis
- Deciphering the Role of Epstein–Barr Virus Latent Membrane Protein 1 in Immune Modulation: A Multifaced Signalling Perspective
- Co-Infections and Superinfections between HIV-1 and Other Human Viruses at the Cellular Level
- Recent advances on anti-HIV CAR-T cell treatment to provide sustained HIV remission
- Post-Hoc Analysis of Potential Correlates of Protection of a Recombinant SARS-CoV-2 Spike Protein Extracellular Domain Vaccine Formulated with Advax-CpG55.2-Adjuvant
- Safety and immunogenicity of the ChAdOx1–MVA-vectored conserved mosaic HIVconsvX candidate T-cell vaccines in HIV-CORE 005.2, an open-label, dose-escalation, first-in-human, phase 1 trial in adults living without HIV-1 in the UK
- Latency-reversing agents: where are we now?
- Evaluating immunotherapy as a pathway toward HIV cure.
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