Poor intracytoplasmic sperm injection outcome in infertile males with azoospermia factor c microdeletions.
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Summary
AZFc microdeletions adversely affect ICSI outcome; patients with AZFc deletion should be informed that they have reduced opportunities to be biological fathers.
- Type
- article
- Published
- 2021-03-18
- Cited by
- 18
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W3136857702
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:232310983
Keywords
Intracytoplasmic sperm injection, Azoospermia factor, Testicular sperm extraction, Azoospermia, Medicine
References
- Gene copy number reduction in the azoospermia factor c (AZFc) region and its effect on total motile sperm count.
- Susceptibility of gr/gr rearrangements to azoospermia or oligozoospermia is dependent on DAZ and CDY1 gene copy deletions
- Comparison of follicular fluid amphiregulin and EGF concentrations in patients undergoing IVF with different stimulation protocols
- Molecular and clinical characterization of Y chromosome microdeletions in infertile men: a 10-year experience in Italy.
- Y chromosome AZFc microdeletion may not affect the outcomes of ICSI for infertile males with fresh ejaculated sperm
- Clinical data and parenthood of 63 infertile and Y-microdeleted men.
- Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte.
- National collection of embryo morphology data into Society for Assisted Reproductive Technology Clinic Outcomes Reporting System: associations among day 3 cell number, fragmentation and blastomere asymmetry, and live birth rate.
- Complications and outcome of assisted reproduction technologies in overweight and obese women.
- The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men
- Effect of hCG priming on embryonic development of immature oocytes collected from unstimulated women with polycystic ovarian syndrome
- Decreased fertilization rate and embryo quality after ICSI in oligozoospermic men with microdeletions in the azoospermia factor c region of the Y chromosome.
- The sperm quality and clinical outcomes were not affected by sY152 deletion in Y chromosome for oligozoospermia or azoospermia men after ICSI treatment.
- AZF microdeletions of the Y chromosome and in vitro fertilization outcome.
- Microdissection TESE: sperm retrieval in non-obstructive azoospermia.
- Detection of sperm in men with Y chromosome microdeletions of the AZFa, AZFb and AZFc regions.
- Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA–binding protein gene
- Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11.
- Laboratory guidelines for molecular diagnosis of Y-chromosomal microdeletions.
- Cumulative live birth rate: time for a consensus?
Cited by
- Intracytoplasmic sperm injection outcomes are comparable in ejaculated sperm but poor in testicular sperm. But why? An opportunity to further understand the AZFc region.
- Male fertility: a review of the publications July — September 2021
- Genetik und männliche Infertilität
- Clinical Outcomes and Live Birth Rate Resulted From Microdissection Testicular Sperm Extraction With ICSI-IVF in Non-Obstructive Azoospermia: A Single-Center Cohort Study
- Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility
- Does ICSI outcome in obstructive azoospermia differ according to the origin of retrieved spermatozoa or the cause of epididymal obstruction? A comparative study
- Controlled ovarian stimulation for endometriosis patients with ultra‐long GnRH‐agonist or GnRH‐antagonist protocols: A retrospective study by propensity score matching
- EAA/EMQN best practice guidelines for molecular diagnosis of Y‐chromosomal microdeletions: State of the art 2023
- Novel predictors for livebirth delivery rate in patients with idiopathic non-obstructive azoospermia based on the clinical prediction model
- Sperm retrieval rate and patient factors in azoospermia factor c microdeletion azoospermia: a systematic review
- Y chromosome microdeletions in Chinese men with infertility: prevalence, phenotypes, and intracytoplasmic sperm injection outcomes
- Y chromosome AZFc microdeletion may have negative effect on embryo euploidy: a retrospective cohort study
- Very severe oligozoospermia with AZFc microdeletion patients may affect intracytoplasmic sperm injection clinical outcomes: A propensity score matching analysis
- Clinical predictors of successful outcomes for couples with nonobstructive azoospermic male partners undergoing micro-TESE
- Independent factors associated with intracytoplasmic sperm injection outcomes in patients with complete azoospermia factor c microdeletions
- Effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection treatment cycle: A single‐center retrospective cohort study
- Cumulative live births and predictive factors of emergency oocyte cryopreservation: a retrospective cohort study
- Impact of AZFc deletion subtypes on sperm retrieval rates via micro-TESE and ICSI outcomes in non-obstructive azoospermia patients
- Additional file 1 of Y chromosome AZFc microdeletion may have negative effect on embryo euploidy: a retrospective cohort study
- Additional file 1 of Y chromosome AZFc microdeletion may have negative effect on embryo euploidy: a retrospective cohort study
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