A meta-analysis of the efficacy and safety of accelerated partial breast irradiation versus whole-breast irradiation for early-stage breast cancer
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Summary
The analysis showed that patients receiving APBI had a higher local recurrence rate, but no differences in distant metastasis, breast cancer deaths, contralateral breast cancer, disease-free survival, and overall survival rates.
- Type
- review
- Published
- 2021-02-02
- Cited by
- 12
- References
- 49
- Access
- Open access
- OpenAlex
- https://openalex.org/W3127793480
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:231778031
Keywords
Medicine, Breast cancer, Meta-analysis, Oncology, Randomized controlled trial
References
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- Irradiation in early-stage breast cancer: conventional whole-breast, accelerated partial-breast, and accelerated whole-breast strategies compared.
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- 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial.
- Sector resection with or without postoperative radiotherapy for stage I breast cancer: five-year results of a randomized trial. Uppsala-Orebro Breast Cancer Study Group.
- Accelerated partial irradiation for breast cancer: systematic review and meta-analysis of 8653 women in eight randomized trials.
- Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO).
- Evidence based radiation oncology: breast cancer.
- Five-year outcomes, cosmesis, and toxicity with 3-dimensional conformal external beam radiation therapy to deliver accelerated partial breast irradiation.
- Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.
- Conservation of the breast using two different radiotherapy techniques: interim report of a clinical trial.
- Is α/β for breast cancer really low?
- Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009).
- Early breast cancer: predictors of breast recurrence for patients treated with conservative surgery and radiation therapy.
- The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials.
- The Christie Hospital breast conservation trial: an update at 8 years from inception.
- Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.
- Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.
- Radiotherapy after breast-conserving surgery in small breast carcinoma: long-term results of a randomized trial.
Cited by
- 5-year results of accelerated partial breast irradiation (APBI) with SBRT (stereotactic body radiation therapy) and exactrac adaptive gating (Novalis®) for very early breast cancer patients: was it all worth it?
- Health-related quality of life of early-stage breast cancer patients after different radiotherapy regimens
- Computed tomography-guided partial-breast brachytherapy using implanted catheters as fiducial markers versus co-registered magnetic resonance imaging.
- Review of recent impacts of artificial intelligence for radiation therapy procedures
- Investigation of the impact of radiotherapy on the shoulder joint by ultrasonography in breast cancer patients
- Recent advances progress in radiotherapy for breast cancer after breast-conserving surgery: a review
- Comparison of partial-breast irradiation and intraoperative radiation to whole-breast irradiation in early-stage breast cancer patients: a Kaplan-Meier-derived patient data meta-analysis
- A Beam Angle Selection Method to Improve Plan Robustness Against Position Error in Intensity-Modulated Radiotherapy for Left-Sided Breast Cancer
- Adjuvant radiotherapy in postmenopausal women with early-stage ER-positive breast cancer: A systematic review and meta-analysis
- Partial breast irradiation after sentinel lymph node biopsy omission: Is it a valid alternative to whole breast Irradiation? Analysis of the dose to the sentinel lymph node region during whole breast irradiation vs. partial breast irradiation
- The evolution of targeted intra operative radiotherapy in early breast cancer
- Ten-year outcomes of 3D-conformal accelerated partial vs. whole breast irradiation after breast-conserving surgery: A randomized study from India.
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