Virtual Docking Screening and QSAR Studies to Explore PI3K and mTOR Inhibitors Acting on AKT in Cancers
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Summary
8 PI3K inhibitors and 11 mTOR inhibitors met the Lipinski and Veber criteria and could be future drugs and were found to have good affinity and interaction with AKT.
- Type
- article
- Published
- 2020-01-01
- Cited by
- 1
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W3116479654
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:235044812
Keywords
PI3K/AKT/mTOR pathway, Protein kinase B, Docking (animal), Chemistry, Phosphorylation
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