Virtual Docking Screening and QSAR Studies to Explore PI3K and mTOR Inhibitors Acting on AKT in Cancers

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Summary

8 PI3K inhibitors and 11 mTOR inhibitors met the Lipinski and Veber criteria and could be future drugs and were found to have good affinity and interaction with AKT.

Type
article
Published
2020-01-01
Cited by
1
References
0
Access
Open access

Keywords

PI3K/AKT/mTOR pathway, Protein kinase B, Docking (animal), Chemistry, Phosphorylation

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