Phosphatidylethanolamine and Phosphatidylserine Synergize To Enhance GAS6/AXL-Mediated Virus Infection and Efferocytosis
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Summary
Efficiency of these processes is enhanced, namely, PE synergizes with PS to promote PS receptor-mediated virus infection and clearance of apoptotic cells and deepen the understanding of how these fundamental biological processes are executed.
- Type
- article
- Published
- 2020-10-28
- Cited by
- 35
- References
- 48
- Access
- Open access
- OpenAlex
- https://openalex.org/W3097795475
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:226039136
Keywords
Efferocytosis, Phosphatidylserine, Biology, GAS6, Phosphatidylethanolamine
References
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- Biology of Zika Virus Infection in Human Skin Cells
- Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses
- The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
- A comparative study of the phospholipids and fatty acids of some insects
- Elevated plasma gas6 levels are associated with venous thromboembolic disease
- Identification of Cell Surface Molecules Involved in Dystroglycan-Independent Lassa Virus Cell Entry
- Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6
- Targeting Inside-Out Phosphatidylserine as a Therapeutic Strategy For Viral Diseases
- Molecular Determinants of Phospholipid Synergy in Blood Clotting
- Phosphatidylserine receptors: enhancers of enveloped virus entry and infection
- Role of Phosphatidylserine Receptors in Enveloped Virus Infection
- Both protein S and Gas6 stimulate outer segment phagocytosis by cultured rat retinal pigment epithelial cells.
- Primary structure of bovine vitamin K-dependent protein S.
- Modulation of Prothrombinase Assembly and Activity by Phosphatidylethanolamine*
- Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein
Cited by
- Development of a blocker of the universal phosphatidylserine- and phosphatidylethanolamine- dependent viral entry pathways
- Phosphatidylserine Receptors Enhance SARS-CoV-2 Infection: AXL as a Therapeutic Target for COVID-19
- The Antiviral Roles of Hydrogen Sulfide by Blocking the Interaction between SARS-CoV-2 and Its Potential Cell Surface Receptors
- Phosphatidylserine receptors enhance SARS-CoV-2 infection
- The interactions of flaviviruses with cellular receptors: Implications for virus entry.
- Hyperinflammation, apoptosis, and organ damage
- m6A Demethylase ALKBH5 Restrains PEDV Infection by Regulating GAS6 Expression in Porcine Alveolar Macrophages
- Lipidomics Revealed Plasma Phospholipid Profile Differences between Deceased and Recovered COVID-19 Patients
- Scramblases and virus infection
- ACE2-Independent Alternative Receptors for SARS-CoV-2
- Gas6/TAM Axis Involvement in Modulating Inflammation and Fibrosis in COVID-19 Patients
- Exploring the Expression and Function of cTyro3, a Candidate Zika Virus Receptor, in the Embryonic Chicken Brain and Inner Ear
- Chikungunya virus entry and infectivity is primarily facilitated through cell line dependent attachment factors in mammalian and mosquito cells
- Targeting Human Proteins for Antiviral Drug Discovery and Repurposing Efforts: A Focus on Protein Kinases
- Receptors and Cofactors That Contribute to SARS-CoV-2 Entry: Can Skin Be an Alternative Route of Entry?
- Single-cell time-resolved multi-omics reveal apoptotic and ferroptotic heterogeneity during foam cell formation
- Amniotic fluid metabolomics identifies impairment of glycerophospholipid and amino acid metabolism during congenital Zika syndrome development
- Lipid alternations in the plasma of COVID-19 patients with various clinical presentations
- Chikungunya Virus Release is Reduced by TIM-1 Receptors Through Binding of Envelope Phosphatidylserine
- Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens
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