Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses
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Summary
A collection of approaches based on SARS-CoV-2 spike-pseudotyped, single-cycle, replication-defective human immunodeficiency virus type-1 (HIV-1) and vesicular stomatitis virus (VSV), as well as a replication-competent VSV/SARS-CoV-2 chimeric virus are described.
- Type
- preprint
- Published
- 2020-06-09
- Cited by
- 589
- References
- 48
- Access
- Open access
- OpenAlex
- https://openalex.org/W3034813551
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:220672111
Keywords
Virology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus disease 2019 (COVID-19), Antibody, Neutralizing antibody
References
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Cited by
- Optimized Pseudotyping Conditions for the SARS-COV-2 Spike Glycoprotein
- COVID-19 Vaccines: “Warp Speed” Needs Mind Melds, Not Warped Minds
- Combined point of care nucleic acid and antibody testing for SARS-CoV-2: a prospective cohort study in suspected moderate to severe COVID-19 disease.
- Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals
- Initial characterisation of ELISA assays and the immune response of the clinically correlated SARS-CoV-2 biobank SERO-BL-COVID-19 collected during the pandemic onset in Switzerland
- Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals
- Longitudinal evaluation and decline of antibody responses in SARS-CoV-2 infection
- Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19
- COVID-19: Mechanisms of Vaccination and Immunity
- D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization
- Prediction of the Receptorome for the Human-Infecting Virome
- Longitudinal analysis of clinical serology assay performance and neutralising antibody levels in COVID19 convalescents
- Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers and convalescent plasma donors: a cohort study using a rapid and sensitive high-throughput neutralization assay
- DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
- Detection, prevalence, and duration of humoral responses to SARS-CoV-2 under conditions of limited population exposure
- High titers of multiple antibody isotypes against the SARS-CoV-2 spike receptor-binding domain and nucleoprotein associate with better neutralization
- Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera
- Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection In Vitro
- Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant
- Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans
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